Original Research
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Recently published articles about Original Research
Original Research
Earlier Use of Paliperidone Palmitate in Patients With Schizophrenia
September 25, 2023
Long-acting injectable antipsychotics (LAIs) are typically reserved for patients with a long history of schizophrenia. This analysis of 3 studies found benefit in initiating the LAI paliperidone palmitate earlier...
Original Research
THC for Neuropsychiatric Symptoms of Dementia
September 18, 2023
Neuropsychiatric symptoms (NPS) in dementia are challenging to manage, and available treatments have a significant side effect profile. This study evaluated the effectiveness of dispensary-obtained tetrahydrocannabinol for patients with...
Original Research
Coprescribing of Z-Drugs and Opioids During COVID-19
September 11, 2023
Coprescribing of nonbenzodiazepine sedative-hypnotics, or “Z-drugs,” with opioids was more common among older patients, although the odds of coprescription among patients overall decreased over the COVID-19 lockdown period.
Original Research
Risk-Sensitive Decision-Making and Self-Harm
September 6, 2023
Greater risk-taking has been associated with suicide attempts in youth with major depression. This study examined whether the association between self-harm and risk-sensitive decision-making is true for bipolar disorder...
Original Research
Safety and Efficacy of Aripiprazole 2-Month Ready-to-Use 960 mg
September 4, 2023
A new formulation of injectable aripiprazole for administration every 2 months showed similar rates of treatment-emergent adverse events to aripiprazole once-monthly 400 mg. Patients in both groups remained clinically...
Original Research
Brexpiprazole in Patients With MDD and Prediabetes
August 28, 2023
Some atypical antipsychotics, while efficacious as adjunctive treatments in major depressive disorder (MDD), can lead to adverse effects and weight gain. Adjunctive brexpiprazole had a limited impact on metabolic...
