Original Research

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Recently published articles about Original Research

PCC
Young Adult Depression, Antidepressant Prescriptions, and Therapy Intensification in the US
Original Research

September 6, 2022

This study evaluated the temporal trend in young adult depression, prescription patterns of first- and second-line antidepressants, and factors influencing therapy intensification for depression stratified by sex.
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JCP
Reasons for Switching Antipsychotic Treatments
Original Research

September 5, 2022

Based on prescription records and prescriber notes, almost half of antipsychotic switches were due to side effects, and women were especially likely to be switched due to intolerability or...
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JCP
Machine Learning Prediction of Suicide Risk
Original Research

August 31, 2022

Suicide assessment prompted by prediction models may be intrusive to patients with no history of suicidality. This study examined if machine learning models identify patients with high suicide risk...
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JCP
Impact of SUD on COVID-19 Outcomes
Original Research

August 29, 2022

Identifying risk factors that predispose individuals to negative COVID-19 outcomes is important. The current study examined the association between substance use disorders, psychiatric diagnosis, and COVID-19–related clinical outcomes.
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JCP
Machine Learning Prediction of ECT Responses
Original Research

August 24, 2022

Predicting individual therapeutic outcomes would be clinically useful to help patients accept electroconvulsive therapy (ECT) for treating depression. This study sought to develop a prediction model for ECT response...
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PCC
Burden of Psychiatric Disorders in Moyamoya Disease
Original Research

August 23, 2022

The objective of this study was to investigate psychiatric comorbidities and trends in patients with Moyamoya disease in the United States.
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JCP
Omega-3 Fatty Acids for MDD With High Inflammation
Original Research

August 22, 2022

This study investigated whether dosage or inflammation levels affect response to omega-3s in MDD patients.
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PCC
Suicide Methods of Depressed and Bipolar Individuals
Original Research

August 16, 2022

This study examined the prevalence of different methods of suicide and self-inflicted poisoning/injury in individuals with major depressive disorder or bipolar disorder.
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JCP
Intravenous Scopolamine Versus Active Placebo in MDD
Original Research

August 15, 2022

Scopolamine, an agent commonly used for motion sickness, has shown promise in treating depression. This study measured its efficacy in major depressive disorder versus an active placebo comparator.
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PCC
Computer Vision Syndrome, Insomnia, and Migraine
Original Research

August 11, 2022

This study assessed the correlation between computer vision syndrome, insomnia, and migraine, using stress as a mediating factor.
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JCP
Remission of Psychotic Late-Life Depression Following ECT
Original Research

August 10, 2022

In this study, ECT was associated with a significantly higher remission rate in psychotic versus nonpsychotic late-life depression.
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PCC
Substance Abuse and Metabolic Syndrome
Original Research

August 9, 2022

This study estimated the prevalence and predictors of metabolic syndrome among substance users in North India.
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Consensus Report on XT Use in Practice

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Figure: Graphic promoting Consensus Report on Xanomeline-Trospium; colorful net design shown with JCP logo in lower left.

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