David R. Spiegel, MD

Department of Psychiatry and Behavioral Sciences, Eastern Virginia Medical School at Old Dominion University, Norfolk, Virginia

24Articles
131.3KReads
2009–2026Active
102Collaborators
89Citations

About

David R. Spiegel, MD, is affiliated with the Department of Psychiatry and Behavioral Sciences at Eastern Virginia Medical School at Old Dominion University. Since 2009, Dr. Spiegel has authored 24 articles focusing on clinical topics including neurology, COVID, addiction, catatonia, delirium, psychotic disorders, rare diseases, and seizures. His publications address cases such as amiodarone-induced thyrotoxicosis, Guillain-Barre syndrome complicated by anxiety, trigeminal neuralgia in multiple sclerosis with opioid use disorder, and N-methyl-D-aspartate receptor antibody encephalitis. Dr. Spiegel frequently collaborates with co-authors Abbey McLean, Faith E. Reid, Ann Ayzman, Ariana Spiegel, and Elizabeth Monter.

Publications

Case Report

Amiodarone-Induced Thyrotoxicosis and Mania

July 28, 2026

A 66-year-old man diagnosed with amiodarone-induced thyrotoxicosis who presented to the emergency department with symptoms of mania.

David R. Spiegel, Rachel Billingsly, Melissa Cazzell, et al

Case Report

Ventilation Weaning, Anxiety, and Valproic Acid

May 28, 2026

The authors present the case of a man with Guillan Barre syndrome, whose mechanical ventilation weaning was prolonged, in part, by anxiety.

David R. Spiegel, Alex LaFever, Ryan Vazquetelles, et al

Case Report

Trigeminal Neuralgia in MS With OUD

October 14, 2025

A 54-year-old woman with MS presented to the ED with a 6-week history of progressively worsening left facial pain. While responsive to opiates, she had a history of OUD.

David R. Spiegel, Janelle Milstead, Rebecca Fetter, et al

Case Report

Shock Anxiety After Electrical Storm Treated With CBT

April 24, 2025

A patient with arrhythmogenic right ventricular dysplasia/cardiomyopathy, who had recently experienced electrical storm from her implantable cardioverter-defibrillator, developed shock anxiety with phobic avoidance.

David R. Spiegel, Alexander Eckstrom

Case Report

Thyrotoxic Psychosis in Graves’ Disease

February 27, 2025

A patient with a 2-year history of Graves’ disease and nonadherent to anti-thyroid treatment developed mania with psychosis.

David R. Spiegel, Trevor Schlecht, Emily Pilc, et al

Case Report

Catatonia in a Patient With Hypothyroidism Due to Levothyroxine Nonadherence

August 1, 2024

This report describes a case of catatonia in the context of a 72-year-old patient with nonadherence to thyroxine who developed severe hypothyroidism.

David R. Spiegel, Conor Jahelka, Morgan Shelton, et al

Case Report

Seizures Due to Anti-NMDAR Encephalitis With Unremarkable Imaging Evaluations

January 11, 2024

Management options for women with anti-NMDAR encephalitis and high clinical probability of ovarian tumor (OT) but negative imaging studies include immunotherapy without further search for OT, repetitive screening for...

David R. Spiegel, Abbey McLean, Megan Ralston, et al

Case Report

Capgras Syndrome After Bifrontal Craniotomy

November 7, 2023

Capgras syndrome is historically rare and was initially thought to be precipitated only by psychodynamic causes; however, it is now a known sequela of organic causes such as neurologic...

David R. Spiegel, Miranda N. Teixeira, Jovanna A. Tracz, et al

Case Report

Ovarian Teratoma–Induced NMDA Receptor Antibody Encephalitis With Psychosis and Catatonia

August 1, 2023

This report describes a case of acute-onset behavioral changes accompanied by psychosis and catatonia in a young woman who was ultimately determined to have NMDA receptor antibody encephalitis.

David R. Spiegel, Kripa Ahuja, Faith E. Reid, et al

Case Report

Psychosis in Multiple Sclerosis

July 25, 2023

A patient with no prior psychiatric or medical history presented to the hospital with acute-onset left facial droop and other stigmata of multiple sclerosis with subacute onset of psychosis.

David R. Spiegel, Shaan S. Sharma, Megan Ralston, et al

Case Report

Differential Diagnosis of Anterograde Amnesia From Bilateral Hippocampal Ischemia Due to Opiate Use

May 9, 2023

A patient with no history of premorbid cognitive deficits was found unconscious in her home and later presented to the emergency department with a clear mentation but dense anterograde...

David R. Spiegel, Faith E. Reid, Marie Isabelle Yrastorza-Daghma, et al

Case Report

Reversal of Symptoms of Catatonic Coma With Lorazepam

February 2, 2023

In this case of catatonic coma, which precipitated a palliative care consult, full-dose lorazepam challenge changed the clinical course.

David R. Spiegel, Kripa Ahuja, Ann Ayzman, et al

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Physicians Postgraduate Press, Inc. (PPP) makes no warranties about the accuracy or completeness of any information published in The Journal of Clinical Psychiatry or other PPP materials, and disclaims liability for any use or non-use of that information. Clinicians should not rely solely on these materials and should exercise their own professional judgment when making patient care decisions on an individualized basis.

David R. Spiegel, MD

About

Publications

Amiodarone-Induced Thyrotoxicosis and Mania