Jennifer L. Vande Voort, MD

Department of Psychiatry and Psychology, Mayo Clinic, Rochester, Minnesota.

  • 12Articles
  • 92.7KReads
  • 2014–2026Active
  • 55Collaborators
  • 329Citations

About

Jennifer L. Vande Voort, MD, is affiliated with the Department of Psychiatry and Psychology at the Mayo Clinic in Rochester, Minnesota. Since 2014, Dr. Vande Voort has published extensively on treatment-resistant depression, including the use of ketamine and esketamine, as well as on suicide prevention and transcranial magnetic stimulation in adolescent depression. Her work also addresses child and adolescent psychiatry, addiction, and the impact of parental opioid use on neonatal and child outcomes. She has collaborated frequently with colleagues such as Balwinder Singh and Paul E. Croarkin.

Publications

JCP
Next-Step Treatment Options for Treatment-Resistant Depression
Consensus Statement

Next-Step Treatment Options for Treatment-Resistant Depression

January 21, 2026

Strong consensus emerged for augmentation with second-generation antipsychotics, TMS, and ketamine/esketamine in the base vignette. Preferences shifted to include non-augmentative antidepressants and ECT based on patient characteristics.
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JCP
Ketamine Reduces Suicidality Associated ED Use in Patients With Treatment-Resistant Depression
Original Research

Ketamine Reduces Suicidality Associated ED Use in Patients With Treatment-Resistant Depression

September 17, 2025

After the acute phase of ketamine treatment, ED visits for suicidal ideation decreased by 84%, and total ED visits for suicidality decreased by 63%.
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JCP
Long-Term Outcomes of IV Ketamine and IN Esketamine in Treatment-Refractory Depression
Original Research

Long-Term Outcomes of IV Ketamine and IN Esketamine in Treatment-Refractory Depression

July 30, 2025

The study results suggest that patients with treatment-resistant depression who are on maintenance treatment require less frequent treatments with IV ketamine compared to IN esketamine.
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JCP
Trajectories of Irritability Improvement in Depressed Adolescents Treated with 1Hz and 10Hz Transcranial Magnetic Stimulation
Original Research

Trajectories of Irritability Improvement in Depressed Adolescents Treated with 1Hz and 10Hz Transcranial Magnetic Stimulation

April 9, 2025

Irritability significantly improved during the course of both 1 Hz and 10 Hz treatments in conjunction with overall depression improvement.
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JCP
Adult Outcomes of Children With Reactive Attachment Disorder
Original Research

Adult Outcomes of Children With Reactive Attachment Disorder

October 18, 2023

Adults who had reactive attachment disorder as children had high rates of psychiatric diagnoses, substance use, suicide attempts, and psychiatric hospitalizations.
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JCP
Ketamine vs Esketamine for TRD
Original Research

Ketamine vs Esketamine for TRD

February 1, 2023

Are ketamine and esketamine equally efficacious? This observational study compares the efficacy of subanesthetic intravenous ketamine with that of intranasal esketamine for treatment-resistant depression in a real-world clinical setting.
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PCC
Original Research

Perinatal Opioid Use and Infant Outcomes

June 10, 2021

This study compared outcomes among newborns of opioid-using and nonopioid drug–using mothers with those of control mothers who did not report substance use. Read on to find out more.
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JCP
Letter to the Editor

BMI and Remission in Depressed Patients Receiving IV Ketamine

November 12, 2019

Few studies have evaluated optimal dosing of intravenous (IV) ketamine for treatment-resistant depression (TRD). This report analyzes data from previous studies of IV ketamine to assess the association between...
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PCC
Original Research

Effects of Parental Opioid Use on Children

August 15, 2019

Most individuals who abuse opioids are of child-rearing age, and knowledge gaps remain regarding how this impacts their offspring. This study evaluated physical and psychiatric diagnoses of children with...
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JCP
Original Research

Sleep and Antisuicidal Response to Ketamine

December 6, 2016

Patients with insomnia and disrupted sleep are at increased risk of suicide. Check out this article to see if researchers found a link between antisuicidal response to ketamine and...
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JCP
Article

Late-Night Wakefulness and Suicidal Ideation

June 22, 2016

Sleep problems have been linked to suicidal thoughts and attempts, but most studies have investigated suicide risk only over long periods of time. Read this article to learn what...
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JCP
Article

Effect of Baseline Anxious Depression on Initial and Sustained Antidepressant Response to Ketamine

September 25, 2014

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Physicians Postgraduate Press, Inc. (PPP) makes no warranties about the accuracy or completeness of any information published in The Journal of Clinical Psychiatry or other PPP materials, and disclaims liability for any use or non-use of that information. Clinicians should not rely solely on these materials and should exercise their own professional judgment when making patient care decisions on an individualized basis.

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