Major Depressive Disorder (MDD) is a debilitating condition characterized by persistent feelings of sadness, hopelessness, and a lack of interest in daily activities. Understanding its underlying causes and effective treatments is crucial for patient well-being. The Journal of Clinical Psychiatry provides a comprehensive look into MDD, offering evidence-based therapeutic approaches and the latest research findings. Our expert editors ensure content is relevant and actionable, aiding psychiatrists in offering holistic care to those grappling with depression.
Depression and Major Depressive Disorder
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Recently published articles about Depression (MDD)
Original Research
Efficacy of Citalopram Treatment in Bipolar Depression
January 12, 2021
Antidepressants are widely used to treat bipolar illness, though their effectiveness in this disorder has not been established. This randomized, double-blind, placebo-controlled trial assessed the efficacy and safety of...
Case Report
Joy Journal: A Behavioral Activation Technique for Depression
January 7, 2021
Here, read about an elderly woman with depression, experiencing hopelessness during the COVID-19 pandemic. A combination of psychotropic medications and a joy journal, a behavioral activation intervention, improved her...
Original Research
Predictors of ECT Treatment Response in Depression
December 15, 2020
Several clinical variables assumed to predict electroconvulsive therapy (ECT) outcome in major depressive disorder are interrelated. This study tries to disentangle this interdependence to distill the most important predictors...
Original Research
Adjunctive Pimavanserin and Sleep/Wakefulness in MDD
December 1, 2020
Adjunctive pimavanserin can reduce depressive symptoms and improve function in patients with major depression and inadequate antidepressant response. This analysis evaluated the effects of adjunctive pimavanserin on sleep/wakefulness disturbances.
