Major Depressive Disorder (MDD) is a debilitating condition characterized by persistent feelings of sadness, hopelessness, and a lack of interest in daily activities. Understanding its underlying causes and effective treatments is crucial for patient well-being. The Journal of Clinical Psychiatry provides a comprehensive look into MDD, offering evidence-based therapeutic approaches and the latest research findings. Our expert editors ensure content is relevant and actionable, aiding psychiatrists in offering holistic care to those grappling with depression.
Depression and Major Depressive Disorder
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Recently published articles about Depression (MDD)
Original Research
Omega-3 Treatment for Depression With Coronary Heart Disease
June 4, 2019
Adjunct treatment with the omega-3 fatty acid eicosapentaenoic acid (EPA) has been shown to increase antidepressant efficacy. This study examined whether adding EPA to sertraline improved response in depressed...
Review Article
Treatment-Resistant Depression Definition and Staging
June 4, 2019
To optimize treatment choices for patients with treatment-resistant depression (TRD), TRD should be defined accurately and unambiguously. This review examines extant descriptions and staging models of TRD and posits...
Clinical and Practical Psychopharmacology
Oral Ketamine for Depression, 1: Pharmacologic Considerations and Clinical Evidence
April 2, 2019
Ketamine has gained visibility recently for its rapid antidepressant effects, but the routes of administration currently in use have drawbacks in terms of cost and inconvenience. In this article,...