This work may not be copied, distributed, displayed, published, reproduced, transmitted, modified, posted, sold, licensed, or used for commercial purposes. By downloading this file, you are agreeing to the publisher’s Terms & Conditions.

Original Research

Antecedents to Panic Disorder in Nonreferred Adults.

Joseph Biederman, MD; Carter R. Petty, MA; Stephen V. Faraone, PhD; Dina R. Hirshfeld-Becker, PhD; Aude Henin, PhD; Lindsay Brauer, BA; Bonnie Kaufman, BA; and Jerrold F. Rosenbaum, MD

Published: August 15, 2006

Article Abstract

Objective: Previous work has shown thatchildhood anxiety disorders are unique antecedents for panicdisorder. The current study examined both childhood and adultcomorbid disorders as potential antecedent disorders to panicdisorder in a large sample of nonreferred adults.

Methods: Subjects were 1018 adults with (N = 58)and without (N = 960) panic disorder who were derived from a sampleoriginally ascertained through family studies of probands withand without attention-deficit/hyperactivity disorder (ADHD); datawere obtained from 1988 to 1996. Classification and regressiontrees (CART) analysis was used to examine anxiety and nonanxietydisorders antecedent to panic disorder.

Results: CART analysis showed that separationanxiety disorder, social phobia, and simple phobia were uniquepredictors of subsequent panic disorder.

Conclusion: These results support and expandpreviously reported findings in referred samples documenting thatcomorbid anxiety disorders are unique antecedent risk factors forpanic disorder.

Volume: 67

Quick Links:

Continue Reading…

Subscribe to read the entire article


Buy this Article as a PDF