This work may not be copied, distributed, displayed, published, reproduced, transmitted, modified, posted, sold, licensed, or used for commercial purposes. By downloading this file, you are agreeing to the publisher’s Terms & Conditions.

Letter to the Editor

Antipsychotic-Induced Sexual Dysfunction and the Strength of the Evidence

Fernando Rico-Villademoros, MD, and Elena P. Calandre, MD

Published: August 15, 2005

Article Abstract

Because this piece has no abstract, we have provided for your benefit the first 3 sentences of the full text.

Sir: Olfson and colleagues1 conclude from a cross-sectionalstudy in 139 outpatients with schizophrenia that sexual dysfunctionis common in men who are treated with olanzapine,risperidone, quetiapine, or haloperidol and is associated withdiminished quality of life and decreased occurrence of romanticrelationships.

Their results concerning rates of sexual dysfunction aresomewhat surprising both because of the high rates encounteredwith olanzapine (54.1%) and quetiapine (50%) and becauseof the lack of differences in impact on sexual functioningamong the antipsychotics under study. We agree with the studylimitations mentioned by the authors: causality based solely onpatients’ attribution, lack of baseline assessment of sexual functioning,and lack of power.

Some JCP and PCC articles are available in PDF format only. Please click the PDF link at the top of this page to access the full text.

Related Articles

Volume: 66

Quick Links: