This work may not be copied, distributed, displayed, published, reproduced, transmitted, modified, posted, sold, licensed, or used for commercial purposes. By downloading this file, you are agreeing to the publisher’s Terms & Conditions.

Articles

Antidepressant-Induced Sexual Dysfunction

Robert Taylor Segraves, M.D., Ph.D.

Published: July 1, 1998

Article Abstract

This article reviews current evidence regarding sexual side effects of antidepressant drugs. Controlledstudies have demonstrated that some antidepressant drugs have adverse effects on orgasm andlibido. Orgasmic dysfunction and ejaculatory delay appear to be common sexual side effects of theserotonin selective reuptake inhibitors (SSRIs). A variety of treatment options are available if a patientexperiences antidepressant-induced sexual dysfunction. Often, modification of the pharmacologic regimenwill restore sexual function while maintaining antidepressant activity. The frequency of sexualside effects reported with the SSRIs mandates that the clinician inquire about sexual function if theseagents are used. Bupropion and nefazodone appear to have an unusually low incidence of sexual sideeffects.


Some JCP and PCC articles are available in PDF format only. Please click the PDF link at the top of this page to access the full text.

Volume: 59

Quick Links: Depression (MDD)

Sign-up to stay
up-to-date today!

SUBSCRIBE

Already registered? Sign In

Original Research

Frontothalamic Circuit Abnormalities in Patients With Bipolar Depression and Suicide Attempts

To identify potential markers for suicide risk, this fMRI study looked at neural activity in bipolar depression...

Read More...