Just Published
Original Research
Artificial Intelligence in Depression – Medication Enhancement (AID-ME): A Cluster Randomized Trial of a Clinical Decision Support System for Personalized Depression Treatment Selection and Management
August 27, 2025
This study provides preliminary evidence that longitudinal use of an AI-enabled clinical decision support system can improve outcomes in MDD.
Original Research
N-acetylcysteine for Co-occurring PTSD and Alcohol Use Disorder: A Double-Blind, Randomized Controlled Trial
August 27, 2025
Among individuals with PTSD and alcohol use disorder receiving CBT and either NAC or placebo, both groups had significant reductions in both PTSD symptom severity and alcohol use, with…
Recent Features
The Journal of Clinical Psychiatry
The Journal of Clinical Psychiatry is a leader in peer-reviewed articles on mental health topics for psychiatrists and medical professionals.
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Original Research
Lumateperone as Adjunctive Therapy in MDD: A Randomized, Double-Blind, Phase 3 Trial
August 25, 2025
In patients with MDD with inadequate antidepressant response, adjunctive lumateperone 42 mg significantly improved depression symptoms and severity versus adjunctive placebo, and it was generally well tolerated.
Original Research
Levomilnacipran, but Not Duloxetine, Inhibits Serotonin and Norepinephrine Reuptake Throughout Its Therapeutic Range
August 25, 2025
Levomilnacipran and duloxetine are both potent serotonin reuptake inhibitors at all therapeutic regimens for MDD. Potent norepinephrine reuptake inhibition can be achieved from initiation with levomilnacipran, in contrast to…
The Primary Care Companion for CNS Disorders
The Primary Care Companion for CNS Disorders seeks to advance the clinical expertise of primary care physicians and other health care professionals who treat patients with mental and neurologic illnesses.
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Recent CME Institute Activities
2025 Manuscript Peer Review for Physicians Postgraduate Press, Inc. (The Journal of Clinical Psychiatry | The Primary Care Companion for CNS Disorders)
Evaluating the Old and New in Alzheimer’s Disease: Today’s Options for Improving Diagnosis and Treatment
Alzheimer’s Disease: New Paths to Treatment
Staying Up to Date in Perinatal Depression: Pathophysiology and Treatment Research
Neuropsychiatric Complications of Parkinson’s Disease Psychosis
Assessing Progress in FSHD Treatment Options: Unraveling Challenges and Measuring Outcomes
