James K. Rustad, MD
Geisel School of Medicine, Dartmouth, Lebanon, New Hampshire; Larner College of Medicine, University of Vermont, Burlington, Vermont; White River Junction VA Medical Center White River Junction, Vermont
Rounds in the General Hospital
Clozapine, Xanomeline-Trospium, and Catatonia
August 11, 2026
Abrupt clozapine discontinuation during a cross-taper to xanomeline/trospium chloride can trigger catatonia. Learn how overlapping cholinergic mechanisms complicate this transition and how to manage withdrawal-induced catatonia.
Rounds in the General Hospital
Strategies for Documenting the Medical Record
May 7, 2026
Documentation should be objective and relevant, especially in psychosocially complex cases—too much information can interfere with establishing the correct diagnosis and treatment plan, while too little increases risk of...