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Neurobehavioral Symptoms and Machado Joseph Disease
Case Report

September 2, 2025

The authors highlight the neuropsychiatric symptomology of Machado Joseph Disease and how management may be approached in older adult patients who might struggle with similar acute-onset psychiatric concerns.
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JCP
Psychedelic Therapies: One Drug, Multiple Treatments: Reply to Modesto-Lowe et al
Letter to the Editor

September 1, 2025

The authors reply to a letter by Modesto-Lowe et al regarding their survey of psychedelic practitioners’ views on psychological support.
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JCP
Toward Consensus in Psychedelic-Assisted Therapy: The Critical Role of Psychotherapeutic Support
Letter to the Editor

September 1, 2025

A recent survey examining psychedelic practitioners’ views on psychological support in psychedelic-assisted therapy is discussed.
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JCP
Five-Year Outcomes of First Suicide Attempts: Lethality, Recurrence, and Mortality
Original Research

September 1, 2025

Recurrence of suicide attempt occurred in 37.2% of patients, with 27.8% having ≥3 attempts. Alcohol use predicted high-lethality first attempts, and female sex predicted multiple reattempts.
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Cannabis-Based Treatment Offers Hope for Insomnia
news

August 29, 2025

A large UK study suggests cannabis-based medicines may ease insomnia, anxiety, and quality-of-life symptoms.
Weekly Mind Reader: N-Acetylcysteine Falls Short
news

August 29, 2025

This week, we revisit N-acetylcysteine with CBT, community care for pregnant patients with catatonia, and a new look at Cushing syndrome.

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Political Polar Opposites? Same Neural Wiring.

Recent Features

The Journal of Clinical Psychiatry

The Journal of Clinical Psychiatry is a leader in peer-reviewed articles on mental health topics for psychiatrists and medical professionals.

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JCP
Artificial Intelligence in Depression – Medication Enhancement (AID-ME): A Cluster Randomized Trial of a Clinical Decision Support System for Personalized Depression Treatment Selection and Management
Original Research

August 27, 2025

This study provides preliminary evidence that longitudinal use of an AI-enabled clinical decision support system can improve outcomes in MDD.
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JCP
N-acetylcysteine for Co-occurring PTSD and Alcohol Use Disorder: A Double-Blind, Randomized Controlled Trial
Original Research

August 27, 2025

Among individuals with PTSD and alcohol use disorder receiving CBT and either NAC or placebo, both groups had significant reductions in both PTSD symptom severity and alcohol use, with…
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The Primary Care Companion for CNS Disorders

The Primary Care Companion for CNS Disorders seeks to advance the clinical expertise of primary care physicians and other health care professionals who treat patients with mental and neurologic illnesses.

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PCC
Predictors of Depression Response in a Community ECT Clinic
Original Research

August 28, 2025

Anxiety symptoms may be a factor correlated with depression treatment response, suggesting potential utility in screening for anxiety symptoms in assessing likelihood of success with ECT treatment.
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PCC
It Takes a Village: A Multidisciplinary Approach to Catatonia in Pregnancy
Case Report

August 26, 2025

Timely treatment of catatonia is crucial and outweighs the risk of exposure to the fetus.
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Recent CME Institute Activities

2025 Manuscript Peer Review for Physicians Postgraduate Press, Inc. (The Journal of Clinical Psychiatry | The Primary Care Companion for CNS Disorders)

2025 Manuscript Peer Review for Physicians Postgraduate Press, Inc. (The Journal of Clinical Psychiatry | The Primary Care Companion for CNS Disorders)
Evaluating the Old and New in Alzheimer’s Disease: Today’s Options for Improving Diagnosis and Treatment

Evaluating the Old and New in Alzheimer’s Disease: Today’s Options for Improving Diagnosis and Treatment
Alzheimer's Disease: New Paths to Treatment

Alzheimer’s Disease: New Paths to Treatment
Staying Up to Date in Perinatal Depression: Pathophysiology and Treatment Research

Staying Up to Date in Perinatal Depression: Pathophysiology and Treatment Research
Neuropsychiatric Complications of Parkinson’s Disease Psychosis

Neuropsychiatric Complications of Parkinson’s Disease Psychosis
Assessing Progress in FSHD Treatment Options: Unraveling Challenges and Measuring Outcomes

Assessing Progress in FSHD Treatment Options: Unraveling Challenges and Measuring Outcomes

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