Duloxetine Alleviates Stimulant Dysphoria, Helps With Enuresis, and Complements Cognitive Response in an Adolescent With Attention-Deficit/Hyperactivity Disorder

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To the Editor: Attention-deficit/hyperactivity disorder (ADHD) is one of the most commonly encountered child and adolescent psychiatry disorders in clinical practice with a worldwide prevalence of 5%. Stimulants are a first-line treatment modality in the ADHD pharmacotherapy guidelines. Yet, 20% to 35% of subjects in clinical trials show inadequate response that could be attributed, in part, to dose-limiting side effects of medications or disorder severity or complexity.