Withdrawal-Emergent Dyskinesia Following Abrupt Discontinuation of Desvenlafaxine

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To the Editor: Tardive dyskinesia (TD) is defined by the DSM-5 as athetoid or choreiform movements of the tongue, lower face, jaw, and extremities. Withdrawal-emergent dyskinesia (WED) is a subtype of TD that appears after discontinuation or reduction in dosage of a medication and is generally limited to 4-8 weeks. WED has been reported with antipsychotics, but despite an extensive literature search of PubMed with keywords, we found no published cases of WED associated with discontinuation of serotonergic-noradrenergic reuptake inhibitors (SNRIs).