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Care Companionfor CNS Disorders

Advancing primary care with essential peer-reviewed research and insights into CNS disorders

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PCC
Complexities of Serotonin Syndrome
Case Report

Complexities of Serotonin Syndrome

December 4, 2025

A 58-year-old man presented to the ED due to muscle stiffness, uncontrollable limb movements, and the sensation as if his body was on fire.
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PCC
Psychosis Screening in Genetic Disorders
Letter to the Editor

Psychosis Screening in Genetic Disorders

December 4, 2025

The author discusses routine monitoring for the development of psychotic symptoms among individuals with rare genetic disorders that confer risk for psychosis.
PCC
Using Digital Technologies to Avoid Doctor’s Orders
Rounds in the General Hospital

Using Digital Technologies to Avoid Doctor’s Orders

December 2, 2025

The availability of portable technologies and application-based services can complicate caretaking in the hospital setting, as patients can circumvent medical recommendations.
, , , et al
PCC
Culturally Adaptive Mental Health Care
Letter to the Editor

Culturally Adaptive Mental Health Care

December 2, 2025

The author discusses the culturally adaptive work of Dr Vidya Sagar, whose mid-20th-century innovations in family-centered care laid the groundwork for India’s unique trajectory in community psychiatry.
PCC
Benzodiazepine-Induced Neurologic Dysfunction
Case Report

Benzodiazepine-Induced Neurologic Dysfunction

November 27, 2025

This case illustrates how benzodiazepine-induced neurologic dysfunction and benzodiazepine use disorder can coexist, emphasizing the importance of distinguishing between them to guide diagnosis and management.
,
PCC
From Varenicline to Neuroleptic Malignant Syndrome
Case Report

From Varenicline to Neuroleptic Malignant Syndrome

November 27, 2025

This case highlights the complexity of diagnosing atypical neuroleptic malignant syndrome in high-risk individuals after sudden cessation of varenicline and cigarette smoking.
,
PCC
Comorbidities Obscure Autism Diagnosis
Case Report

Comorbidities Obscure Autism Diagnosis

November 25, 2025

A 14-year-old boy with longstanding psychotic illness, posttraumatic stress from adverse social experiences, and suicidality presented for neuropsychiatric assessment.
PCC
Sequelae of Toxic Exposures in Veterans
Rounds in the General Hospital

Sequelae of Toxic Exposures in Veterans

November 25, 2025

A 45-year-old veteran has ongoing symptoms likely related to past exposure to burn pits, dust storms, airborne industrial pollutants, and head trauma from hard parachute landings.
, , , et al
PCC
Impact of Patient Suicide on Mental Health Professionals
Original Research

Impact of Patient Suicide on Mental Health Professionals

November 20, 2025

Patient suicide can cause lasting emotional and professional distress in mental health professionals due to their unique relationship with the patient.
, , , et al
PCC
Psychosis or Multiple System Atrophy?
Case Report

Psychosis or Multiple System Atrophy?

November 20, 2025

A 67-year-old woman presented with altered mental status, hallucinations, and hyperalgesia of the bilateral lower legs and was subsequently diagnosed with multiple system atrophy.
, , , et al
PCC
Religious Preoccupation in Adolescence
Case Report

Religious Preoccupation in Adolescence

November 18, 2025

A 16-year-old boy developed new-onset psychosis of religious preoccupation and delusions.
, , , et al
PCC
Clozapine Withdrawal–Induced Catatonia
Case Report

Clozapine Withdrawal–Induced Catatonia

November 18, 2025

A patient with treatment-resistant schizophrenia developed persistent catatonia after sudden cessation of clozapine, highlighting the challenges in management and the potential role of clozapine reintroduction.
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