The Primary
Care Companionfor CNS Disorders

Advancing primary care with essential peer-reviewed research and insights into CNS disorders

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More Articles from The Primary Care Companion for CNS Disorders

PCC
Machine Madness: A Case of Artificial Intelligence Psychosis
Case Report

Machine Madness: A Case of Artificial Intelligence Psychosis

December 30, 2025

A 41-year-old man with a history of substance-induced psychosis, developed symptoms of psychosis related to frequent occupational use of AI.
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PCC
A Case of Kratom Withdrawal
Case Report

A Case of Kratom Withdrawal

December 25, 2025

A 29-year-old man experienced kratom withdrawal that necessitated intensive care management and resulted in subsequent cardiac arrest.
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PCC
Diagnosis and Management of Rage
Rounds in the General Hospital

Diagnosis and Management of Rage

December 23, 2025

This article offers a practical framework for distinguishing rage from irritability and impulsivity, identifying underlying neuropsychiatric drivers, and guiding evidence-based management across conditions including PTSD, TBI, and mood disorders.
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PCC
Clozapine-Induced Corrected QT-Interval Prolongation and Relationship With Serum Clozapine Concentration
Case Report

Clozapine-Induced Corrected QT-Interval Prolongation and Relationship With Serum Clozapine Concentration

December 18, 2025

The author presents a case of clozapine-induced QTc prolongation and discusses its relationship with serum clozapine concentration
PCC
Balancing Pragmatism and Ethics in Psychiatry
Case Report

Balancing Pragmatism and Ethics in Psychiatry

December 16, 2025

A psychiatrist strategically used a patient’s internalized fear of extremism to redirect behavior during a manic episode.
PCC
Facilitating Academic Success for Clinicians
Rounds in the General Hospital

Facilitating Academic Success for Clinicians

December 16, 2025

Many clinicians, experience “imposter syndrome,” which can foster the false belief that they are unqualified for promotion.
, , , et al
PCC
Bupropion for Postpartum Depression and Narcolepsy
Case Report

Bupropion for Postpartum Depression and Narcolepsy

December 11, 2025

Bupropion was an effective pharmacologic therapy for narcolepsy with cataplexy in a 21-year-old woman with postpartum depression.
, , , et al
PCC
Unstable Lithium Levels in a Bodybuilder With Bipolar Disorder
Case Report

Unstable Lithium Levels in a Bodybuilder With Bipolar Disorder

December 11, 2025

This case highlights the importance of assessing dietary habits, supplement use, and potential anabolic steroid use, particularly in physically active patients undergoing lithium therapy.
, ,
PCC
Tetrabenazine-Induced Suicidality
Case Report

Tetrabenazine-Induced Suicidality

December 9, 2025

A 19-year-old male with schizophrenia and obsessive-compulsive disorder developed acute suicidality after starting treatment with low-dose tetrabenazine.
,
PCC
Is It Huntington Disease or Tardive Dyskinesia?
Case Report

Is It Huntington Disease or Tardive Dyskinesia?

December 9, 2025

A 59-year-old woman with a psychiatric history and prolonged olanzapine use has worsening abnormal movements, weight loss, and behavioral changes. She was previously diagnosed with TD.
, , , et al
PCC
A Case of AVM, Hemichorea, and Depression
Case Report

A Case of AVM, Hemichorea, and Depression

December 4, 2025

A 30-year-old man presented with rapid, involuntary jerky movements on his right side, exacerbated by stress and absent during sleep, as well as low mood, hopelessness, poor concentration, anhedonia,…
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PCC
Complexities of Serotonin Syndrome
Case Report

Complexities of Serotonin Syndrome

December 4, 2025

A 58-year-old man presented to the ED due to muscle stiffness, uncontrollable limb movements, and the sensation as if his body was on fire.
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