Psychotic Disorders

Psychotic disorders, including schizophrenia, are characterized by delusions, hallucinations, and disorganized thinking. The Journal of Clinical Psychiatry offers comprehensive insights into these disorders, from their neurobiological underpinnings to evidence-based therapeutic strategies. Our expert editors ensure content is both actionable and holistic, aiding psychiatrists in offering comprehensive care to individuals with psychotic disorders.

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Recently published articles about Psychotic Disorders

PCC
7-OH-Mitragynine–Induced Psychosis
Case Report

7-OH-Mitragynine–Induced Psychosis

April 14, 2026

The authors present the case of a patient who developed psychosis and delirium following several months of heavy 7-OH use that persisted for nearly a week following cessation.
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JCP
Correlates and Predictors of Criminal Legal Involvement in First-Episode Psychosis
Original Research

Correlates and Predictors of Criminal Legal Involvement in First-Episode Psychosis

March 30, 2026

More than 10% of people with first-episode psychosis are involved in the legal system before (11%) and while (14%) receiving mental health treatment, which can interrupt access to specialty...
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PCC
Between Crisis and Clarity: Steroid-Induced Psychosis in Addison Disease
Case Report

Between Crisis and Clarity: Steroid-Induced Psychosis in Addison Disease

March 24, 2026

This case highlights a rare but clinically significant dilemma: balancing essential corticosteroid replacement against neuropsychiatric toxicity.
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PCC
Psychosis and Kratom
Letter to the Editor

Psychosis and Kratom

March 10, 2026

The authors discuss the possible association between psychosis and kratom use.
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PCC
Calcineurin Inhibitor–Induced Psychosis
Case Report

Calcineurin Inhibitor–Induced Psychosis

February 17, 2026

The authors report a case of delayed and recurrent calcineurin inhibitor–induced psychosis with both tacrolimus and cyclosporine, highlighting the need to better understand host vulnerability and risk stratification.
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Psychosis Soars in Younger Generations
news

Psychosis Soars in Younger Generations

February 10, 2026

A large study finds that psychosis diagnoses are rising sharply – and appearing earlier – among younger generations.
JCP
Clinical pearls of early use of Xanomeline–Trospium in the in-patient setting with Michael Halassa MD, PhD
Podcast

Clinical pearls of early use of Xanomeline–Trospium in the in-patient setting with Michael Halassa MD, PhD

February 10, 2026

Dr. Halassa shares clinical insights on xanomeline-trospium for inpatient schizophrenia, addressing negative symptoms and treatment-resistant cases.
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JCP
Developing Algorithmic Psychiatry with Michael Halassa MD, PhD
Podcast

Developing Algorithmic Psychiatry with Michael Halassa MD, PhD

January 27, 2026

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Where Autoantibodies Strike in Anti-NMDAR Encephalitis
news

Where Autoantibodies Strike in Anti-NMDAR Encephalitis

January 26, 2026

A new study shows that antibodies in anti-NMDAR encephalitis target exposed hotspots on NMDA receptors, explaining synaptic disruption.
JCP
Rethinking Amisulpride: Could N-Methylation Result in a New and Even Better Antipsychotic?
ASCP Corner

Rethinking Amisulpride: Could N-Methylation Result in a New and Even Better Antipsychotic?

January 26, 2026

This article will familiarize US clinicians with amisulpride’s history and data, and the rationale behind development of LB-102, an N-methylated analogue of amisulpride.
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How Delusions Take Shape
news

How Delusions Take Shape

January 22, 2026

A new study finds that early psychosis delusions emerge as emotionally grounded, embodied responses shaped by lived experience and relationships.
PCC
Cotard Syndrome in Schizophrenia
Case Report

Cotard Syndrome in Schizophrenia

January 8, 2026

A 42-year-old woman with schizophrenia and multiple prior hospitalizations presented with worsening psychosis and physical aggression toward her mother.
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