Sofia E. Matta, MD

Department of Psychiatry, Harvard Medical School, Boston, Massachusetts; Massachusetts General Hospital, Boston, Massachusetts

PCC
Diagnosing and Treating Impulsivity
Rounds in the General Hospital

February 5, 2026

Impulsivity is a characteristic of many psychiatric and neuropsychiatric conditions throughout the lifespan; however, in older adults it frequently signals an emerging neurodegenerative process.
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PCC
Diagnosis and Management of Rage
Rounds in the General Hospital

December 23, 2025

This article offers a practical framework for distinguishing rage from irritability and impulsivity, identifying underlying neuropsychiatric drivers, and guiding evidence-based management across conditions including PTSD, TBI, and mood disorders.
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PCC
Sequelae of Toxic Exposures in Veterans
Rounds in the General Hospital

November 25, 2025

A 45-year-old veteran has ongoing symptoms likely related to past exposure to burn pits, dust storms, airborne industrial pollutants, and head trauma from hard parachute landings.
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PCC
Psychological Sequelae of Drone Attacks
Rounds in the General Hospital

November 6, 2025

Read about a newly emerging form of combat stress, one shaped by the relentless and psychologically corrosive nature of modern drone warfare.
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PCC
Serious Suicide Attempt Management
Rounds in the General Hospital

July 8, 2025

Approximately half of the individuals who take their own life have had contact with their primary care provider within the month before their death.
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PCC
Facing Intensive Care: A Guide for PCPs
Rounds in the General Hospital

June 17, 2025

Critically ill patients develop complex problems that involve affective, behavioral, cognitive, and motor manifestations, and failure to attend to these signs and symptoms can jeopardize the safety of both...
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PCC
Multimodal Approaches to Pain Management
Rounds in the General Hospital

June 3, 2025

Although the primary objective of managing acute pain is to provide effective pain relief, it is also important to minimize medication side effects, improve patient function, and reduce the...
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PCC
Sequelae of Adverse Childhood Experiences
Rounds in the General Hospital

May 6, 2025

Long-term complications of ACEs involve psychiatric and medical conditions, such as mood and substance use disorders, chronic heart and lung diseases, obesity, diabetes, cancer, and PTSD.
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PCC
Comorbid Bipolar Disorder and PTSD
Rounds in the General Hospital

December 24, 2024

Bipolar disorder and PTSD are highly comorbid conditions, and pharmacologic management poses unique challenges, as side effects of the commonly used medications for one disorder can worsen the symptoms...
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PCC
Treatment of Pain in the Context of Alcohol and Substance Use Disorders
Rounds in the General Hospital

October 17, 2024

When prescribing opioids for pain, prescription monitoring programs should be checked, regular urine toxicology screening should be conducted, and patients with an opioid use disorder should receive FDA-approved medication...
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PCC
Pharmacologic Management of TBI
Rounds in the General Hospital

July 16, 2024

Cognitive complaints, including difficulties with attention, concentration, and memory, are common in patients post-TBI; however, many medications have been studied in the treatment of cognition after TBI. Read on...
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Consensus Report on XT Use in Practice

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Figure: Graphic promoting Consensus Report on Xanomeline-Trospium; colorful net design shown with JCP logo in lower left.

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