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Letter to the Editor

Alternative Pharmacotherapy for Trichotillomania: A Report of Successful Bupropion Use

Nadeem H. Bhanji, BSc(Pharm), MD; Howard C. Margolese, MD, CM, MSc, FRCP(C)

Published: September 1, 2004

Article Abstract

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Sir: Trichotillomania is classified in the spectrum of impulsecontrol disorders, with phenomenological overlap with obsessive- compulsive disorder (OCD), tic, and affective spectrum disorders.1,2 The role of serotonin has been postulated in trichotillomania based on overlapping features with OCD and positive treatment response observed with selective serotonin reuptake inhibitors (SSRIs) in open-label studies.3,4 In controlled studies, however, not all patients have benefited from SSRIs.5,6

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