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Letter to the Editor

The Emergence of Darkness Phobia in a Bipolar Patient During Quetiapine Treatment

Maria Teresa Plana, MD; Anna Mane, MD; Antoni Benabarre, PhD, MD; Jose M. Goikolea, MD; and Eduard Vieta, PhD, MD

Published: April 15, 2006

Article Abstract

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Sir: Worsening or emergence of anxiety symptoms induced by atypical antipsychotics has been reported in the literature, especially obsessive-compulsive symptoms.1 Most of these cases have been described in schizophrenic patients. It is unclear how treatment with atypical antipsychotics may induce these symptoms, although a secondary serotonergic and dopaminergic dysfunction has been hypothesized.2‘ ‹’ ‹

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