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Letter to the Editor

Lack of Association Between Plasma Apolipoprotein E and Suicide Attempts

Enrique Baca-Garcia MD, Carmen Diaz-Sastre MD, Eloy Garcí­a-Resa MD, Antonio Ceverino MD, Antonio Ramirez MD, Jeronimo Saiz-Ruiz MD, and Jose de Leon MD

Published: April 1, 2004

Article Abstract

Because this piece does not have an abstract, we have provided for your benefit the first 3 sentences of the full text.

Sir: Low cholesterol may be associated with increased suicide attempt risk.1,2 Apolipoprotein E is a plasma protein that serves as a ligand for the low-density lipoprotein receptors and, through its interaction with these receptors, participates in cholesterol transport.3 No published studies have explored the association between plasma apolipoprotein E and suicide. This study compared plasma apolipoprotein E levels in 298 suicide attempters seen in the emergency room and 258 controls.

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