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Letter to the Editor

Mirtazapine for Alcohol Dependence: A Case Report

David N. Crockford, MD, and William D. White, MD

Published: April 15, 2005

Article Abstract

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Sir: While alcohol dependence is highly prevalent, pharmacotherapyoptions for its management remain relatively limited1or underutilized.2 Mirtazapine is indicated for the symptomatictreatment of depression. We report a case in which mirtazapineaided the treatment of a depressed alcoholic man, speculatingthat its 5-HT3 antagonism may have contributed to its beneficialeffect on his alcoholism.’ ‹

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