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Letter to the Editor

Monosymptomatic Hypochondriacal Psychosis: Atypical Presentation and Response to Olanzapine

Prabhat K. Chand, MD, DNB; Sandip Anand, MBBS; and Pratima Murthy, DPM, MD

Published: June 15, 2005

Article Abstract

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Sir: Monosymptomatic hypochondriacal psychosis (MHP)is an illness characterized by a single delusion of somatic typethat can present at any age from late adolescence onward,equally affecting both sexes and having a poor prognosis withouttreatment.1 Infestation with parasites, body dysmorphophobia,and halitosis are the most commonly reported somaticdelusions.1 Pimozide has been frequently used and reported tobe effective in the treatment of MHP, but has the potential for undesirable side effects including tardive dyskinesia and cardiacconduction defects.1‘ ‹’ ‹

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