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Letter to the Editor

New-Onset Diabetes Mellitus Associated With the Initiation of Quetiapine Treatment

Maxwell Sobel, Eric D. Jaggers, and Michael A. Franz

Published: August 1, 1999

Article Abstract

Letter to the Editor

Sir: Quetiapine is a novel antipsychotic that antagonizes
both serotonergic (5-HT1A and 5-HT2) and dopaminergic (D1
and D2) receptors. The manufacturer describes hypoglycemia,
hyperglycemia, and diabetes mellitus as infrequent side effects
(0.1%-1.0%). The following is a case report of possible quetiapine-
induced onset of diabetes mellitus.

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