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JCP
Differentiating Subtypes of MDD Using Serum Biomarkers
Original Research

June 23, 2025

Significant differences in biomarker profiles were observed across MDD subtypes: the melancholic subtype showed higher cortisol levels and lower serotonin levels, and the atypical subtype showed elevated levels of…
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JCP
Bright Light Therapy in the Morning or Midday for Nonseasonal Depression in Bipolar Disorder
Original Research

June 23, 2025

Bright light therapy is well tolerated in bipolar disorder, starting at 45 minutes/day, with only 6% of patients experiencing a hypomanic switch and 13% experiencing subsyndromic symptoms, which resolved…
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JCP
Association Between Adult Sexual Assault and Psychiatric Disorders: Results From NESARC
Original Research

June 16, 2025

Among participants who experienced adult sexual assault, 85.25% had at least 1 lifetime psychiatric disorder. In women, the strongest associations were with PTSD, borderline personality disorder, and suicide attempts,…
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Vol 86 • 2025 • Number 2

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Original Research

Incidence and Risk Factors for Suicide Attempt During Pregnancy and Postpartum

Original Research

Valbenazine in Elderly Adults With Tardive Dyskinesia

Academic Highlights

Optimizing Treatment With Aripiprazole Monohydrate: Pharmacokinetic Advantages of Long-Acting Injectable Formulations, A Consensus Panel Report

Original Research

Older Adults Visiting Emergency Departments for Mental Health Issues:A CHIRPP Database Study

Consensus Statement

Developing a Treatment-Resistant Depression Consultation Program, Part I: Practical and Logistical Considerations

Brief Report

Psychosocial Correlates of Optimism among US Military Veterans
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Focus on Psychosis Focus on Geriatric Psychiatry Focus on Women’s Mental Health Focus on Suicide Early Career Psychiatrists Focus on Psychotherapy

Original Research

JCP
Cognitive Behavioral Therapy for Insomnia with Prolonged Exposure Compared to Sleep Hygiene and Prolonged Exposure
Original Research

June 4, 2025

On average, participants had reductions in PTSD symptoms, with no differences between the treatment groups. CBT for insomnia with prolonged exposure produced greater reductions in insomnia symptoms and increases…
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JCP
Risk of Alzheimer’s Disease and Vascular Dementia in Patients With Peripheral Vestibular Disorders
Original Research

June 2, 2025

The authors found that peripheral vestibular disorders are a risk factor for dementia, regardless of psychiatric comorbidities.
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JCP
Detecting Tardive Dyskinesia Using Video-based AI
Original Research

May 28, 2025

The algorithm reliably detected suspected tardive dyskinesia, reaching higher sensitivity and specificity than trained raters using the standard assessment.
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Review Articles

JCP
Treating PTSD in Military Populations
Meta-Analysis

March 24, 2025

Integrating psychotherapies and pharmacotherapies may address multiple dimensions of PTSD more effectively than monotherapies.
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JCP
Changes in Cognition in Patients With Schizophrenia
Meta-Analysis

September 25, 2024

Only marginal improvements in cognition were seen over time; the greatest were achieved for patients with an illness duration shorter than 10 years.
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JCP
Economic Impact of Cognitive Impairment and Negative Symptoms in Schizophrenia
Review Article

August 21, 2024

Patients with schizophrenia and cognitive impairment had a 100% increase in relapse-related hospitalizations and ER visits versus patients with no (or only mild) cognitive impairment.
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JCP
Cognitive Effects of ECT in Schizophrenia: A Review
Review Article

June 5, 2024

ECT was not associated with any significant cognitive deficits in people with treatment-resistant schizophrenia across global cognition, attention, language, visuospatial function, and executive function domains. The majority of studies…
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JCP
Interpersonal Psychotherapy for PTSD: A Critical Review
Review Article

May 29, 2024

This critical review will give clinicians confidence in considering IPT as an alternative to exposure treatments for posttraumatic stress disorder.
JCP
Omega-3 PUFA Supplements for ADHD
Meta-Analysis

August 30, 2023

Although omega-3 polyunsaturated fatty acids (PUFAs) may not improve core symptoms of attention-deficit/hyperactivity disorder, longer-term PUFA supplementation may have potential benefits.
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Read articles from ASCP Corner

ASCP Corner

Letters to the Editor

JCP
Erecting Barriers to Suicide by Removing Barriers to Science
Letter to the Editor

April 30, 2025

The authors comment on the implications of a recent NSF communication warning researchers about the use of certain terms in grant proposals and publications made possible with government funding.
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JCP
The Need for Clinical Guidance on Ketamine/Esketamine Use in Clinical Settings
Letter to the Editor

February 5, 2025

The authors comment on a recent study by Santucci et al.
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JCP
Opioid Use Disorder in Sexually and Gender Diverse Populations: Can We Do Better?
Letter to the Editor

February 3, 2025

The authors respond to a recent JCP article by McDowell and colleagues.
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JCP
Mental Health Assessment and Psychosocial Intervention in Maternal-Fetal Interventions
Letter to the Editor

November 18, 2024

In discussing a recent JCP letter to the editor, Akerson et al recommend that centers for fetal diagnosis and treatment include a social worker who can provide psychosocial assessment,…
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JCP
Clarification Regarding the Psychiatrist’s Role—Reply to Akerson et al
Letter to the Editor

November 18, 2024

The authors respond to a letter by Akerson et al.
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JCP
Detecting Misuse of Prescription Opioids
Letter to the Editor

October 21, 2024

The authors discuss the difficulty in screening for opioid misuse and the need for clinicians to gain confidence in initiating difficult discussions with patients on long-term opioid treatment.
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Commentaries

JCP
Lower Risk of Cardiovascular Disorders in Antidepressant-Treated Women Veterans: Encouraging Findings but Concerns Remain
Commentary

May 7, 2025

Comments on a study by Sumner et al that followed 609,546 women veterans for a mean of 8.8 years to look at associations of antidepressants with incident CVD.
JCP
Benefits and Risks of New Tests for Alzheimer’s Disease
Commentary

April 14, 2025

The authors discuss the limitations and the potential value of blood-based biomarker testing in the detection and diagnosis of Alzheimer’s disease.
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JCP
Investigation of Appetite Hormones Illustrates Current Limitations of Psychiatric Diagnosis
Commentary

April 9, 2025

Commenting on an article by Hsu and colleagues, Dr Mischoulon discusses the current state and future potential of biomarkers in the understanding and treatment of mood disorders.
JCP
Eating Disorders Among Transgender and Gender Diverse People: Qualitative Analysis of Reddit Threads
Commentary

March 10, 2025

This subreddit analysis characterizes the body dissatisfaction and desire to eliminate gendered physical characteristics that transgender and gender diverse (TGD) people with eating disorders experience. Many on the subreddit…
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JCP
A New Tool to Refine Lithium Therapy: Simple Formula for a Complex Problem
Commentary

March 3, 2025

The authors consider potential benefits and limitations of a new equation for estimating 12-hour serum lithium levels.
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JCP
Back to the Office: The Room Where It Happens?
Commentary

March 3, 2025

The authors discuss in-person versus remote delivery of psychotherapy and present the findings of a survey characterizing current practice.
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More JCP Articles

JCP
Schizophrenia, Antipsychotic Drugs, and Risk of Breast Cancer
Clinical and Practical Psychopharmacology

June 16, 2025

This article examines recent meta-analyses and observational studies on breast cancer risk in women with schizophrenia, especially in the context of treatment with first generation and second generation antipsychotics
JCP
What Clinicians Should Know About the Pragmatic Use of Xanomeline-Trospium Combination
ASCP Corner

June 9, 2025

This article will help familiarize clinicians with practical issues in the use of xanomeline-trospium and its entry into the pharmacopoeia for schizophrenia.
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JCP
Administering Semaglutide With Long-Term Olanzapine Use
Case Report

June 9, 2025

This report describes use of the GLP-1R agonist semaglutide in a patient with schizophrenia and severe, olanzapine-induced weight gain that was resistant to alternative treatments.
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JCP
The Dopamine-3 Receptor in the Treatment of Schizophrenia: Part 1
Insights

June 6, 2025

In Part I of his video, Dr. Ragy Girgis highlights the D3 receptor as a promising target in schizophrenia, with potential to address negative and cognitive symptoms unmet by…
JCP
The Dopamine-3 Receptor in the Treatment of Schizophrenia: Part 2
Insights

June 6, 2025

In Part II of his video, Dr. Ragy Girgis examines D3 receptor binding by antipsychotics and its potential to improve negative symptoms in schizophrenia.
JCP
What Is Meant by the Term “Deprescribing,” and Does It Belong in Our Lexicon?
ASCP Corner

June 2, 2025

The authors encourage the field to destigmatize the term “deprescribing” from its misappropriated usage, explicate its accurate definition, and reclaim its purposeful meaning.
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JCP
Idiopathic Hypersomnia: Recognition and Management in Psychiatric Practice
Narrative Review

June 2, 2025

Idiopathic hypersomnia, characterized by excessive daytime sleepiness (EDS), has an estimated population prevalence up to 1.5%. Psychiatric medications may exacerbate EDS and, conversely, idiopathic hypersomnia treatments may exacerbate psychiatric…
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JCP
Outpatient Ketamine Prescribing Practices in Psychiatry in the US: A Nationwide Survey Study
Original Research

May 26, 2025

There is significant variability in ketamine treatment in the community including indications, treatment duration, formulation, and setting of use. Increased oversight and specific practice guidelines are needed to ensure…
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JCP
Prediction Of Adolescent Suicidal Events By Residual Depressive Symptoms
Original Research

May 21, 2025

Sleep disturbance and suicidal ideation were the strongest predictors of hospitalization, and, together with anhedonia, they consistently predicted suicidal events during follow-up.
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JCP
Postpartum Distress in Women With and Without ADHD
Original Research

May 19, 2025

Women with ADHD were 1.14 times more likely to be diagnosed with mood disorder at 6 weeks postpartum and 1.21-1.24 times more likely to be diagnosed with a mood,…
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JCP
Delirium as a Precursor to Dementia in Type 2 DM Patients
Original Research

May 19, 2025

Type 2 diabetes mellitus patients with delirium had a dementia incidence of 42.75%, compared to 22.66% in those without delirium, with a clear dose-response relationship of higher dementia risk…
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JCP
Autism Spectrum Disorder, 2: Imprecision of the Numerical Value of Risk When Examining Predictors of Risk in Regression
Clinical and Practical Psychopharmacology

May 14, 2025

The article examines how different procedures and approaches in analysis of the same data result in different odds ratio values. Also explained is how to evaluate a patient’s risk…

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