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Letter to the Editor

Rebound Psychiatric and Physical Symptoms After Gabapentin Discontinuation

Gabriela Corá-Locatelli, Benjamin D. Greenberg, Juliet D. Martin, and Dennis L. Murphy

Published: March 15, 1998

Article Abstract

Sir: Serotonin reuptake inhibitors (SRIs) offer the most effective pharmacologic treatment for obsessive-compulsive disorder (OCD). Since few patients have a complete response, there is a compelling need for augmentation strategies. We initiated a pilot study to evaluate whether gabapentin might be a useful augmenting agent in a group of patients with OCD (Corá- Locatelli G, Greenberg BD, Martin JD, et al. 1997. Unpublished data).

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