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Letter to the Editor

Reply to Comment on “Lithium and Clozapine Rechallenge: A Retrospective Case Analysis.”

Richard A. Kanaan, MRCPsych

Published: April 16, 2007

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Sir: We are grateful to Dr. Esposito for his comments on distinguishing benign from malignant neutropenia. We agree that tests to distinguish the two may be of considerable benefit to clinical decision making where continuing with clozapine is a possibility. However, as our article1 describes, the rules in the United Kingdom are quite strict about clozapine prescription, so that persevering with clozapine despite the occurrence of a neutropenia is not normally possible.’ ‹

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Volume: 68

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