Back to top Open menu arrow
Download PDF Reprints

The Journal of
Clinical Psychiatry
Free access

The Journal of Clinical Psychiatry

Letter to the Editor May 15, 2005

Development of Subtle Psychotic Symptoms With Memantine: A Case Report

; ; ; ;

J Clin Psychiatry 2005;66(5):658-659

Article Abstract

Because this piece has no abstract, we have provided for your benefit the first 3 sentences of the full text.

Sir: Memantine is a medication that has been recentlyapproved in the United States for the treatment of moderateto-severe Alzheimer’s disease. It is a low-to-moderate affinity,noncompetitive N-methyl-D-aspartate (NMDA) antagonist.1The use of other noncompetitive NMDA antagonists such asketamine and phencyclidine is known to produce psychoticsymptoms.2,3‘ ‹

Also from JCP

NNT, NNH, and LLH for Aripiprazole Once-Monthly in Schizophrenia Effects of Experimental Intermittent Theta Burst Stimulation on Negative Symptoms of Schizophrenia Validation for the Tardive Dyskinesia Impact Scale, a Patient-Reported Outcome Measure in Valbenazine Clinical Trials

From the Editors

New Series The JCP Podcast A third-trimester blood test may identify who is at high risk for postpartum depression before symptoms start, opening the door to prevention instead of waiting for a crisis. The episode also unpacks why zuranolone and brexanolone are not “just benzodiazepines” — and why that mechanistic difference matters clinically.

 

About the Authors

This PDF is free for all visitors!

Cover features March 2026 issue highlighting articles on psychiatric drugs, peer interventions for perinatal depression, and metformin.

Vol 87 • 2026 • Number 1

Read the Current Issue

Original Research

Innovation in Psychiatric Drug Development: A Quantitative Analysis of FDA-Approved Psychiatric Drugs, 2012–2024

Meta-Analysis

Effectiveness of Peer-Administered Interventions for Perinatal Depression or Anxiety

Original Research

Effect of Adjuvant Metformin on Adherence to and Persistence of Treatment With SGAs in Nondiabetic Patients

Editorial

Thank You to the JCP Community

Editorial

Psychotherapy: Integral to Clinical Psychiatry

Original Research

Trends in Benzodiazepine Prescribing to Adults in the United States
View current Issue

Insightful. Evidence-based. Human-centered.

Listen to the JCP Podcast Now
Figure: Digital illustration shows a human head with neural connections and podcast title over a dark blue patterned background.

Subscribe to read
more articles

Subscribe