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Educational Activity

Treating Depression Complicated by Comorbid Medical Illness or Anxiety

Madhukar H. Trivedi, MD; Anita H. Clayton, MD; and Ellen Frank, MD

Published: January 15, 2007

Article Abstract

In this online activity, Trivedi discusses pharmacotherapy treatments fordepression in the presence of comorbid medical illness or physical symptoms. Thefocus is on key aspects of treatment such as remission as the treatment goal,effects of different classes of antidepressants, and benefits of usingtreatment algorithms. Clayton addresses issues related to comorbid depressionand anxiety including prevalence and recognition, risk factors and outcomes,and treatment considerations. Frank highlights the importance of psychotherapyin the treatment of complicated depression, citing empirically validatedpsychotherapies for acute depressive episodes as well as describing how toapply psychotherapy to medical patients with depression

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