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Educational Activity

Treating Partial Responders to Antidepressant Treatment

Madhukar H. Trivedi, MD

Published: September 15, 2009

This CME activity is expired. For more CME activities, visit
Find more articles on this and other psychiatry and CNS topics:
The Journal of Clinical Psychiatry
The Primary Care Companion for CNS Disorders

Article Abstract

Many patients with major depressive disorder only partially respond to initial antidepressant treatment. Residual depressive symptoms need to be addressed so that patients can achieve full remission and return to presymptomatic levels of functioning. This case vignette presents Ms M, a 26-year-old woman who continues to experience depression, fatigue, and sleepi’ ‹ness after adequate antidepressant therapy, and discusses pharmacologic strategies to relieve residual symptoms.

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