Original Research

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Recently published articles about Original Research

JCP
Esmethadone in Patients With Major Depressive Disorder and Inadequate Response to Standard Antidepressants
Original Research

June 17, 2024

Although this trial of esmethadone did not meet its primary outcome, some secondary and post hoc outcomes were promising.
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JCP
Cigarette Smoking and Tobacco Use Disorder Among US Adults
Original Research

June 12, 2024

The prevalence of daily smoking with tobacco use disorder (TUD) was 10 times that of daily cigarette smoking without TUD. But even nondaily smoking can produce or sustain TUD,...
, , , et al
JCP
Pharmacogenetic Phenotypes in a Perinatal Mental Health Clinic
Original Research

June 10, 2024

In patients of childbearing age who have had atypical responses or side effects to antidepressants, pharmacogenomic testing may be considered to guide dose or choice of agent. Dose adjustments...
, , , et al
JCP
Accounting for Differences in Incident Guideline Discordant Prescribing for PTSD Among Women and Men Veterans
Original Research

June 5, 2024

Women Veterans with PTSD were 67% more likely to initiate a guideline discordant medication. More than half of this effect was explained by bipolar disorder, age, and prior psychiatric...
, , , et al
JCP
Depressive Symptom Trajectory and Body Mass Index in Women
Original Research

June 3, 2024

Women with persistently high levels of depressive symptoms had an escalating risk of both underweight and obesity over the 6 years of follow-up.
, , , et al
JCP
Sleep Duration as a Predictor of Suicidal Desire and Intent: An Ecological Momentary Assessment Study
Original Research

June 3, 2024

Both fewer hours of typical sleep and decreases in sleep in an individual night compared to one’s norm may be acute indicators of increased suicide risk.
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