Vol 28, No 2 | Primary Care Companion for CNS Disorders

Original Research

Depression and Cardiovascular Burden in Aging Populations: Insights From the National Health and Nutrition Examination Survey 2010–2020 on Symptom Frequency, Sociodemographic Disparities, and Modifiable Risk Factors

Prim Care Companion CNS Disord 2026;28(2):25m04116

Faizan Ahmed, MD; Ali Imam Awan, MD; Omar Kamel, SPT; Nida Waheed, MBBS; Zaima Afzaal, MBBS; Kainat Aman, MBBS

Original Research

Efficacy and Tolerability of Ultra–Low-Dose Mirtazapine in Adult Chronic Insomnia

Prim Care Companion CNS Disord 2026;28(2):25m04074

Rony Berbara, MD; Kamal Gandotra, MD; Elizabeth Zink, MAS; Matthew Fuller, PharmD; Brigid Wilson, PhD; Meera Kumari, MBBS; Kuldeep Vaghela, MD; Amal Rubai, MD; Trevor Shaver, PA; Rawad EL Ghoul, MD; George Jaskiw, MD; Kingman Strohl, MD

Rounds in the General Hospital

Administering Electroconvulsive Therapy to Critically Ill Individuals: Risks, Monitoring, and Benefits

Prim Care Companion CNS Disord 2026;28(2):25f04072

Samah Ibrahim, MD; Drew Cumming, MD; Gregg A. Robbins-Welty, MD; Kimberly Bond, MD; Katerina Mastronardi, MD; Joseph D. Dragonetti, MD; Kamalika Roy, MD; Melissa P. Bui, MD; Khalid Salaheldin, MD; Javier Lorenzo, MD; Michael Henry, MD; Theodore A. Stern, MD

Case Report

Caffeine for the Treatment of Aseptic Immune Checkpoint Inhibitor–Induced Encephalitis

Prim Care Companion CNS Disord 2026;28(2):25cr04080

Brandon J. Goodwin, DO; Dan Yacubovich, BS; Fatimah B. Alhassan, BS; Rachael Martino, BS; Richard Fagbemigun, MD; Taraneh Alahdadi, MBA, MS; Jessica Pam Engle, DO

Case Report

Atypical Misophonia With Psychiatric Comorbidities in a Medical Student: A Case From a Low-Resource Setting

Prim Care Companion CNS Disord 2026;28(2):25cr04064

Palwasha Asghar, MBBS

Letter to the Editor

Psychosis and Kratom: Rare but Real?

Prim Care Companion CNS Disord 2026; 28(2):25lr04109

Vania Modesto-Lowe, MD, MPH; Tobias Patel, PA-S2

Volume 28 • 2026 • 2

Original Research

Depression and Cardiovascular Burden in Aging Populations: Insights From the National Health and Nutrition Examination Survey 2010–2020 on Symptom Frequency, Sociodemographic Disparities, and Modifiable Risk Factors

Efficacy and Tolerability of Ultra–Low-Dose Mirtazapine in Adult Chronic Insomnia

Rounds in the General Hospital

Administering Electroconvulsive Therapy to Critically Ill Individuals: Risks, Monitoring, and Benefits

Case Report

Caffeine for the Treatment of Aseptic Immune Checkpoint Inhibitor–Induced Encephalitis

Atypical Misophonia With Psychiatric Comorbidities in a Medical Student: A Case From a Low-Resource Setting

Letter to the Editor

Psychosis and Kratom: Rare but Real?

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Volume 28 • 2026 • 2

Original Research

Depression and Cardiovascular Burden in Aging Populations: Insights From the National Health and Nutrition Examination Survey 2010–2020 on Symptom Frequency, Sociodemographic Disparities, and Modifiable Risk Factors

Efficacy and Tolerability of Ultra–Low-Dose Mirtazapine in Adult Chronic Insomnia

Rounds in the General Hospital

Administering Electroconvulsive Therapy to Critically Ill Individuals: Risks, Monitoring, and Benefits

Case Report

Caffeine for the Treatment of Aseptic Immune Checkpoint Inhibitor–Induced Encephalitis

Atypical Misophonia With Psychiatric Comorbidities in a Medical Student: A Case From a Low-Resource Setting

Letter to the Editor

Psychosis and Kratom: Rare but Real?

Consensus Report on XT Use in Practice

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