The Primary
Care Companionfor CNS Disorders

Volume 28 • 2026 • 2

Meta-Analysis

Role of Transcranial Direct Current Stimulation in the Management of Autism Spectrum Disorder in Children and Adolescents: A Systematic Review and Meta-Analysis

Prim Care Companion CNS Disord 2026;28(2):25r04049

Monika Singh, MD, GDCE; Mahwish Adnan, MD; Karrar Husain, MD; Chintan Trivedi, MD, MPH; Shailesh Jain, MD, MPH, MEPH

Original Research

Substance Use Referrals Among Inpatients With Serious Mental Illness: Clinical Characteristics and Real-World Evaluation of the New Hampshire Hospital Screening and Referral Algorithm

Prim Care Companion CNS Disord 2026;28(2):25m04110

Cornel N. Stanciu, MD; Patricia Timmons, MSN, RN; Jeffrey C. Fetter, MD; Manuel Cano, PhD

Original Research

Attitudes of Emergency Department Nurses Toward Violent Patients With Mental Illness

Prim Care Companion CNS Disord. 2026;28(2):25m04081

N. A. Uvais, MBBS, DPM; A. M. Ashfaq U. Rahman, MD; P. Shihabudheen, MD

Original Research

Health Belief Model and Treatment Adherence in Patients With Dissociative Disorders: A Cross-Sectional Study

Prim Care Companion CNS Disord 2026;28(2):25m04085

Sajal Baig, MBBS; Humza Sajjad, MBBS; Tamveel Mehmood, MBBS; Rida Eman, MBBS; Salwa Anwar, MBBS; Ashish Sarangi, MD, DABPN

Original Research

Efficacy and Tolerability of Ultra–Low-Dose Mirtazapine in Adult Chronic Insomnia

Prim Care Companion CNS Disord 2026;28(2):25m04074

Rony Berbara, MD; Kamal Gandotra, MD; Elizabeth Zink, MAS; Matthew Fuller, PharmD; Brigid Wilson, PhD; Meera Kumari, MBBS; Kuldeep Vaghela, MD; Amal Rubai, MD; Trevor Shaver, PA; Rawad EL Ghoul, MD; George Jaskiw, MD; Kingman Strohl, MD

Original Research

Depression and Cardiovascular Burden in Aging Populations: Insights From the National Health and Nutrition Examination Survey 2010–2020 on Symptom Frequency, Sociodemographic Disparities, and Modifiable Risk Factors

Prim Care Companion CNS Disord 2026;28(2):25m04116

Faizan Ahmed, MD; Ali Imam Awan, MD; Omar Kamel, SPT; Nida Waheed, MBBS; Zaima Afzaal, MBBS; Kainat Aman, MBBS

Rounds in the General Hospital

Strategies to Formulate, Present, and Document Complex Cases and Avoid Critical Omissions

Prim Care Companion CNS Disord 2026;28(2):25f04076

Anita K. Chang, DO; Patrick A. Ho, MD, MPH; James K. Rustad, MD; Eileen McGarry, MD; Diana Fox, MD; Theodore A. Stern, MD

Rounds in the General Hospital

Dealing With Dyspnea: Strategies for Patients and Their Family Members

Prim Care Companion CNS Disord. 2026;28(2):25f04094

Joseph D. Dragonetti, MD; Kamalika Roy, MD; Maureen K. Cassady, MD; Michalla Braford, DO; Dona A. Kiriella, MD; Samah Ibrahim, MD; Yelizaveta Sher, MD; Theodore A. Stern, MD

Rounds in the General Hospital

Administering Electroconvulsive Therapy to Critically Ill Individuals: Risks, Monitoring, and Benefits

Prim Care Companion CNS Disord 2026;28(2):25f04072

Samah Ibrahim, MD; Drew Cumming, MD; Gregg A. Robbins-Welty, MD; Kimberly Bond, MD; Katerina Mastronardi, MD; Joseph D. Dragonetti, MD; Kamalika Roy, MD; Melissa P. Bui, MD; Khalid Salaheldin, MD; Javier Lorenzo, MD; Michael Henry, MD; Theodore A. Stern, MD

Brief Report

Recreational Ketamine-Induced Uropathy: Recognition and Management in Primary Care and Psychiatric Practice

Prim Care Companion CNS Disord 2026;28(2):25br04121

Raphael J. Leo, MA, MD; Shelby L. Blaes, PhD; Mubeen A. Jaffri, MD; Stacy M. Fleming, PMHNP; Jennifer A. Galvano, EdD, CASAC-A

Case Report

Coexistence of Mesial Temporal Sclerosis and Juvenile Myoclonic Epilepsy

Prim Care Companion CNS Disord 2026;28(2):25cr04138

Bariscan Mengeliboga, BS; Merve B. Ucar, MD; Ipek Midi, MD

Case Report

Dose-Dependent Valproic Acid–Induced Hyperkalemia

Prim Care Companion CNS Disord 2026;28(2):25cr04124

Francisco S. Silva, MD; Inês S. Braz, MD

Case Report

Functional Neurological Disorder in a Patient With Schizoaffective Disorder: Challenges in Diagnosis, Management, and Disposition

Prim Care Companion CNS Disord 2026;28(2):25cr04035

Waez Umer, BS; Mariam Imtiaz, MBBS; Fauzia Arain, MD; Najeeb Hussain, MBBS

Case Report

Intentional Nonsuicidal Succinylcholine Use in a Health Care Worker With Posttraumatic Stress Disorder

Prim Care Companion CNS Disord 2026;28(2):25cr04075

Vinit Patel, DM; Gurveen Kaur, MD; Piyali Mandal, MD; Dalim Kumar Baidya, MD; Alok Agrawal, MD; Atul Ambekar, MD

Case Report

Bupropion-Dextromethorphan Is a Potential Treatment Combination for Clinically Challenging Apathy

Prim Care Companion CNS Disord 2026;28(2):25cr04112

Wisam Al Jumaili, MD; Nibras Al Gburi, MD; Shailesh Jain, MD; Arif Khan, MD; Lian Al Jumaili

Case Report

Postpartum Obsessive-Compulsive Disorder With Compulsive Digital Picture Taking and Video Recording

Prim Care Companion CNS Disord 2026;28(2):25cr04092

Julia Kaster, DO; Darby DeFord, BS; Elizabeth Ann Cunningham, DO

Case Report

Caffeine for the Treatment of Aseptic Immune Checkpoint Inhibitor–Induced Encephalitis

Prim Care Companion CNS Disord 2026;28(2):25cr04080

Brandon J. Goodwin, DO; Dan Yacubovich, BS; Fatimah B. Alhassan, BS; Rachael Martino, BS; Richard Fagbemigun, MD; Taraneh Alahdadi, MBA, MS; Jessica Pam Engle, DO

Case Report

Between Crisis and Clarity: Steroid-Induced Psychosis in Addison Disease

Prim Care Companion CNS Disord 2026;28(2):25cr04122

Vinod Xavier, DNB; Renji Jos, MD; Roshan Salahudeen, MBBS

Case Report

An Atypical Presentation of Autoimmune Encephalitis

Prim Care Companion CNS Disord 2026;28(2):25cr04083

Skylar Luu, MD; Yu Kong, MD; Mario Sokolic, MD; Elizabeth Chern, MD; Zeshawn Ali, DO; Eric Rutkowski, MD

Case Report

Mania as a Symptom of Hypertensive Emergency in Cerebral Amyloid Angiopathy

Prim Care Companion CNS Disord 2026;28(2):25cr04097

Erin Becker, MD; Vijai Kumar, Dharla, MD; Ilma Chowdhury, DO; Mackenzie Budd, DO; Peter Karalis, MD

Case Report

Tacrolimus-Induced Parasomnia Posttransplantation

Prim Care Companion CNS Disord 2026;28(2):25cr04108

Diego Nolasco, MD; Cara House, MD; Richard Czuma, MD; Brandon Janssen, MD; Matthew Gunther, MD; Shixie Jiang, MD

Case Report

Reversible Clozapine-Induced Antiphospholipid Syndrome

Prim Care Companion CNS Disord 2026;28(2):25cr04042

Joana Regala, MD, MSc; Rita André, MD; João Reis, MD

Case Report

Atypical Misophonia With Psychiatric Comorbidities in a Medical Student: A Case From a Low-Resource Setting

Prim Care Companion CNS Disord 2026;28(2):25cr04064

Palwasha Asghar, MBBS

Letter to the Editor

Psychopharmacotherapy Updates

Prim Care Companion CNS Disord 2026;28(2):25lr04088

Ahmed Naguy, MBBch, MSc, MRCPsych (UK); Nadyah Alayadhi, BSc (Pharma, UK), MSc, PhD (UK); Saxby Pridmore, MD, FRANZCP; Bibi Alamiri, MD, ScD, ABPN

Letter to the Editor

Psychosis and Kratom: Rare but Real?

Prim Care Companion CNS Disord 2026; 28(2):25lr04109

Vania Modesto-Lowe, MD, MPH; Tobias Patel, PA-S2

Volume 28 • 2026 • 2

Meta-Analysis

Role of Transcranial Direct Current Stimulation in the Management of Autism Spectrum Disorder in Children and Adolescents: A Systematic Review and Meta-Analysis

Original Research

Substance Use Referrals Among Inpatients With Serious Mental Illness: Clinical Characteristics and Real-World Evaluation of the New Hampshire Hospital Screening and Referral Algorithm

Attitudes of Emergency Department Nurses Toward Violent Patients With Mental Illness

Health Belief Model and Treatment Adherence in Patients With Dissociative Disorders: A Cross-Sectional Study

Efficacy and Tolerability of Ultra–Low-Dose Mirtazapine in Adult Chronic Insomnia

Depression and Cardiovascular Burden in Aging Populations: Insights From the National Health and Nutrition Examination Survey 2010–2020 on Symptom Frequency, Sociodemographic Disparities, and Modifiable Risk Factors

Rounds in the General Hospital

Strategies to Formulate, Present, and Document Complex Cases and Avoid Critical Omissions

Dealing With Dyspnea: Strategies for Patients and Their Family Members

Administering Electroconvulsive Therapy to Critically Ill Individuals: Risks, Monitoring, and Benefits

Brief Report

Recreational Ketamine-Induced Uropathy: Recognition and Management in Primary Care and Psychiatric Practice

Case Report

Coexistence of Mesial Temporal Sclerosis and Juvenile Myoclonic Epilepsy

Dose-Dependent Valproic Acid–Induced Hyperkalemia

Functional Neurological Disorder in a Patient With Schizoaffective Disorder: Challenges in Diagnosis, Management, and Disposition

Intentional Nonsuicidal Succinylcholine Use in a Health Care Worker With Posttraumatic Stress Disorder

Bupropion-Dextromethorphan Is a Potential Treatment Combination for Clinically Challenging Apathy

Postpartum Obsessive-Compulsive Disorder With Compulsive Digital Picture Taking and Video Recording

Caffeine for the Treatment of Aseptic Immune Checkpoint Inhibitor–Induced Encephalitis

Between Crisis and Clarity: Steroid-Induced Psychosis in Addison Disease

An Atypical Presentation of Autoimmune Encephalitis

Mania as a Symptom of Hypertensive Emergency in Cerebral Amyloid Angiopathy

Tacrolimus-Induced Parasomnia Posttransplantation

Reversible Clozapine-Induced Antiphospholipid Syndrome

Atypical Misophonia With Psychiatric Comorbidities in a Medical Student: A Case From a Low-Resource Setting

Letter to the Editor

Psychopharmacotherapy Updates

Psychosis and Kratom: Rare but Real?

ELSEWHERE:

FOLLOW US:

Volume 28 • 2026 • 2

Meta-Analysis

Role of Transcranial Direct Current Stimulation in the Management of Autism Spectrum Disorder in Children and Adolescents: A Systematic Review and Meta-Analysis

Original Research

Substance Use Referrals Among Inpatients With Serious Mental Illness: Clinical Characteristics and Real-World Evaluation of the New Hampshire Hospital Screening and Referral Algorithm

Attitudes of Emergency Department Nurses Toward Violent Patients With Mental Illness

Health Belief Model and Treatment Adherence in Patients With Dissociative Disorders: A Cross-Sectional Study

Efficacy and Tolerability of Ultra–Low-Dose Mirtazapine in Adult Chronic Insomnia

Depression and Cardiovascular Burden in Aging Populations: Insights From the National Health and Nutrition Examination Survey 2010–2020 on Symptom Frequency, Sociodemographic Disparities, and Modifiable Risk Factors

Rounds in the General Hospital

Strategies to Formulate, Present, and Document Complex Cases and Avoid Critical Omissions

Dealing With Dyspnea: Strategies for Patients and Their Family Members

Administering Electroconvulsive Therapy to Critically Ill Individuals: Risks, Monitoring, and Benefits

Brief Report

Recreational Ketamine-Induced Uropathy: Recognition and Management in Primary Care and Psychiatric Practice

Case Report

Coexistence of Mesial Temporal Sclerosis and Juvenile Myoclonic Epilepsy

Dose-Dependent Valproic Acid–Induced Hyperkalemia

Functional Neurological Disorder in a Patient With Schizoaffective Disorder: Challenges in Diagnosis, Management, and Disposition

Intentional Nonsuicidal Succinylcholine Use in a Health Care Worker With Posttraumatic Stress Disorder

Bupropion-Dextromethorphan Is a Potential Treatment Combination for Clinically Challenging Apathy

Postpartum Obsessive-Compulsive Disorder With Compulsive Digital Picture Taking and Video Recording

Caffeine for the Treatment of Aseptic Immune Checkpoint Inhibitor–Induced Encephalitis

Between Crisis and Clarity: Steroid-Induced Psychosis in Addison Disease

An Atypical Presentation of Autoimmune Encephalitis

Mania as a Symptom of Hypertensive Emergency in Cerebral Amyloid Angiopathy

Tacrolimus-Induced Parasomnia Posttransplantation

Reversible Clozapine-Induced Antiphospholipid Syndrome

Atypical Misophonia With Psychiatric Comorbidities in a Medical Student: A Case From a Low-Resource Setting

Letter to the Editor

Psychopharmacotherapy Updates

Psychosis and Kratom: Rare but Real?

Insightful. Evidence-based. Human-centered.

Subscribe to readmore articles

Subscribe to read
more articles