The Primary
Care Companionfor CNS Disorders

Advancing primary care with essential peer-reviewed research and insights into CNS disorders

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More Articles from The Primary Care Companion for DNS Disorders

PCC
An Update on the Future of Wilson Disease Management
Commentary

November 29, 2022

Due to Wilson disease myriad manifestations, its rarity, and its range of symptoms, differential diagnosis may be challenging, leading to delays in treatment. This Neuroscience Commentary reviews diagnostic acumen…
PCC
High-Dose Therapy in Treatment-Refractory Psychosis
Original Research

November 24, 2022

In forensic patients hospitalized in a long-term psychiatric facility, antipsychotic dose reduction had a positive effect on treatment effectiveness, competency restoration, and hospital discharge with no symptom relapse.
PCC
Therapeutic Dilemma of Wake-up Stroke
Original Research

November 24, 2022

The importance of recognizing wake-up stroke for early referral to acute stroke care is highlighted in this study, as patients may benefit from acute reperfusion therapy after obtaining the…
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PCC
Impairment of Sexual Desire in Treatment-Resistant Depression
Original Research

November 22, 2022

Patients with treatment-resistant depression had a high prevalence of sexual desire impairment, which was associated with male sex and higher depressive symptom severity.
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PCC
Recreational Use of 2M2B
Case Report

November 22, 2022

This report describes a patient whose use of 2-methyl-2-butanol—an inexpensive, easily accessible, potent, and nondetectable ethanol substitute—led to protracted intoxication and delirium.
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PCC
COVID-19–Associated Benzodiazepine-Resistant Catatonia Responds to Amantadine
Case Report

November 17, 2022

This case highlights the successful use of amantadine in benzodiazepine-resistant catatonia associated with COVID-19 infection.
, , , et al
PCC
Sertraline-Induced Urinary Retention in an Adolescent
Case Report

November 17, 2022

This case report is of a teenaged boy with impaired micturition brought on by the 5-HT2 activity of an SSRI that was reversed by the alpha-2 antagonist properties of…
, , , et al
PCC
Low COVID-19 IgG Titers After Vaccination and Breakthrough Infection in Patients on Clozapine
Case Report

November 15, 2022

This report highlights 2 cases of patients taking clozapine who were vaccinated for COVID-19 and had breakthrough infections yet demonstrated markedly decreased antibody responses during the testing sweep.
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PCC
New-Onset Psychosis After COVID-19 Vaccine
Case Report

November 15, 2022

A 45-year-old woman with no psychiatric history developed psychosis after receiving the COVID-19 vaccine. This report highlights that history of recent vaccine administration as a potential etiology deserves consideration…
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PCC
Hypertensive Emergency in a Patient With Anxiety
Rounds in the General Hospital

November 10, 2022

Hypertensive emergencies can be difficult to diagnose and manage, and various neuropsychiatric manifestations can arise during such a crisis.
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PCC
Autoimmune Encephalitis Following TBI
Case Report

November 10, 2022

A 50-year-old man, who had recently sustained a severe TBI, was brought to the hospital with acute psychiatric symptoms, prompting consideration of a diagnosis of autoimmune encephalitis. This report…
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PCC
Boredom, Loneliness, and Smartphone Addiction Among Young Adults
Original Research

November 8, 2022

In this study, smartphone addiction was significantly associated with higher boredom proneness, anxiety, and loneliness.
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