Psychedelics

Psychedelics in psychiatry: emerging research on psilocybin, MDMA and ketamine. Clinical evidence, treatment protocols and therapeutic potential.

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Recently published articles about Psychedelics

LSD Microdosing Doesn’t Appear to Help Treat Adult ADHD
news

March 19, 2025

A recent clinical trial found that microdosing LSD offers no significant benefit over a placebo in improving ADHD symptoms in adults.
JCP
Maintenance of Antidepressant Effect After 1 Dose of Psilocybin
Original Research

March 3, 2025

Over 52 weeks, a single administration of 25 mg psilocybin suggested longer maintenance of antidepressant effect than both 1 mg and 10 mg.
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JCP
Psychological Support in Psychedelic Therapy
Original Research

February 5, 2025

The survey reveals differences of opinion among psychedelic researchers, with a slight trend toward preference for an emotive approach to psychological support.
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Weekly Mind Reader: Clinicians Tackle Psychedelics
news

October 18, 2024

This week offers a deep dive into psychedelics, ADHD fluctuations, and efforts to curb adolescent inhalant use.
PCC
Talking to Your Patients About Psychedelics
Rounds in the General Hospital

October 15, 2024

Given the precipitous increase in both scientific publications and public interest in psychedelics, clinicians should learn more about how they work, what they might work for, and what their...
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JCP
SSRI Discontinuation and AUD Relapse
Case Report

August 26, 2024

A man with AUD achieves sobriety on treatment with an SSRI and naltrexone, but then stops taking the SSRI to participate in a psilocybin “ceremony.” What factors contributed to...
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JCP
Functional Unblinding in Pivotal Studies and the Future of Psychedelic Medicine
Commentary

August 21, 2024

Dr Rosenbaum comments on the challenge of evaluating trials of treatments whose effects are unmistakable, and how this dilemma may be addressed.
Researchers Uncover How Psilocybin Works in the Brain
news

July 18, 2024

Psilocybin disrupts brain networks related to reflective thinking, offering potential therapeutic benefits for mental health issues.
PCC
Medical Uses and Adverse Effects of Psilocybin
Rounds in the General Hospital

May 28, 2024

There has been a resurgence of interest in the use of psychedelics, including psilocybin, for therapeutic purposes, with early studies suggesting promise for use in various conditions such as...
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Weekly Mind Reader: Exploring the Connection Between Psilocybin and Serotonin
news

March 1, 2024

The Primary Care Companion has published research that examines the relationship between psilocybin and some brain chemicals.
PCC
Psilocybin and the Development of Serotonin Toxicity
Case Report

February 29, 2024

This case revealed that unregulated and recreational use of psilocybin in the setting of polypharmacy demonstrates a potential risk for serotonin toxicity that should be diligently monitored.
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PCC
Psychedelic Microdosing and Mental Health
Systematic Review

January 16, 2024

There is a growing body of evidence suggesting a positive correlation between psychedelic microdosing and improved mental well-being.
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