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What Clinicians Should Know About the Pragmatic Use of Xanomeline-Trospium Combination
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This article will help familiarize clinicians with practical issues in the use of xanomeline-trospium and its entry into the pharmacopoeia for schizophrenia.
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Administering Semaglutide With Long-Term Olanzapine Use
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This report describes use of the GLP-1R agonist semaglutide in a patient with schizophrenia and severe, olanzapine-induced weight gain that was resistant to alternative treatments.
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The Dopamine-3 Receptor in the Treatment of Schizophrenia: Part 1
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In Part I of his video, Dr. Ragy Girgis highlights the D3 receptor as a promising target in schizophrenia, with potential to address negative and cognitive symptoms unmet by...

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The authors describe a case in which cocaine-induced cardiac toxicity initially masked β-blocker (carvedilol) toxicity and suggest improvements in management for similar cases.
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Excited Catatonia in Opioid and Benzodiazepine Withdrawal
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A 37-year-old man developed excited catatonia in the setting of concurrent opioid and benzodiazepine withdrawal, requiring high dosages of benzodiazepines to resolve.
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Featured Article Research

How Patients Talk May Matter More Than What They Say
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June 9, 2025

A new study suggests that subtle language cues in how patients talk about their mental health may reveal critical, often overlooked insights.
Restrictive Diets Could Make Depression Worse
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Restrictive diets could make depressive symptoms worse, suggesting that one-size-fits-all eating plans could carry hidden mental health risks.
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As we head into the summer months, we consider a better approach to chronic pain, explore idiopathic hypersomnia, and wonder about the practice of deprescribing.

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