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When Obsession and Psychosis Become Indistinguishable
September 8, 2026
Differentiating obsessions from delusions is essential for accurate diagnosis and management, as comorbid obsessive-compulsive symptoms in schizophrenia complicate treatment and may influence cognitive and affective outcomes.
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Case Report
Oral Glutamatergic Modulation with Dextromethorphan and Piracetam for Refractory Bipolar Disorder With OCD
February 23, 2026
Three patients with combined bipolar disorder and OCD experienced remission of depressive, anxious, and obsessive-compulsive symptoms after piracetam was added to dextromethorphan.
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Cannabis Use and Time to Psychiatric Rehospitalization: A Survival Analysis
September 28, 2026
In young adults with psychotic or bipolar disorders, cannabis use is a predictor of early psychiatric readmission. The first 3 months post-discharge are critical for follow-up and intervention.
Author Insights
Combining Clozapine and Xanomeline/Trospium Chloride: Mechanisms of Action and the Genesis of Catatonia
September 25, 2026
Warren Cheng, MD Candidate, on a case where abruptly stopping clozapine while continuing Cobenfy (xanomeline-trospium) preceded severe catatonia, and the rebound-cholinergic hypothesis that may explain the risk as Cobenfy...