Case Report

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PCC
ECT for Psychosis in Huntington Disease-Like 2
Case Report

May 19, 2026

A 47-year-old woman with genetically confirmed Huntington disease-like 2 had refractory psychosis and functional decline but responded well to electroconvulsive therapy.
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PCC
Adjunct Memantine for Inappropriate Sexual Behavior
Case Report

May 14, 2026

Two patients with intellectual disability and major neurocognitive disorder exhibited inappropriate sexual behavior that significantly decreased after memantine was added as adjunctive therapy.
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PCC
From Physical to Digital: Hoarding Phenomena in Obsessive-Compulsive Disorder
Case Report

May 14, 2026

This case illustrates how hoarding phenomenology can manifest in digital environments, which offer virtually unlimited storage, anonymity, and low visibility.
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PCC
Aripiprazole-Induced Pathological Gambling
Case Report

May 7, 2026

A 27-year-old man with a history of substance abuse developed a new-onset compulsive gambling pattern within weeks of starting aripiprazole.
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PCC
Clozapine-Associated Pulmonary Embolism
Case Report

May 5, 2026

A 48-year-old woman with schizoaffective disorder taking clozapine developed acute pulmonary embolism despite negative D-dimer results.
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PCC
Polydipsia-Related Hyponatremia in Autism
Case Report

April 30, 2026

The authors present the case of a 10-year-old boy with autism who presented to the ED with hyponatremia-related seizures due to compulsive water drinking.
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Oral Glutamatergic Modulation with Dextromethorphan and Piracetam for Refractory Bipolar Disorder With OCD
Case Report

February 23, 2026

Three patients with combined bipolar disorder and OCD experienced remission of depressive, anxious, and obsessive-compulsive symptoms after piracetam was added to dextromethorphan.
JCP
Zuranolone for Postpartum Depression in Real-World Clinical Practice
Case Report

July 2, 2025

Three cases of successful treatment of postpartum depression with zuranolone are presented and discussed.
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JCP
Administering Semaglutide With Long-Term Olanzapine Use
Case Report

June 9, 2025

This report describes use of the GLP-1R agonist semaglutide in a patient with schizophrenia and severe, olanzapine-induced weight gain that was resistant to alternative treatments.
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Dose-Dependent Valproic Acid–Induced Hyperkalemia
Case Report

April 9, 2026

The authors present the case of a young man with bradycardia and Jacobs syndrome, in which a clear, dose-dependent relationship between valproic acid and hyperkalemia was observed.
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PCC
Succinylcholine Misuse in a Health Care Worker
Case Report

April 7, 2026

A health care worker with a history of PTSD and substance use misused succinylcholine for stress relief and sleep, highlighting the risks of occupational access to high-risk medications among...
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PCC
Managing FND and Psychiatric Illness
Case Report

April 7, 2026

This case of a 54-year-old woman with schizoaffective disorder illustrates how stigma around psychiatric conditions can impact patient disposition, particularly in patient populations with complex neurological disorders.
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Featured Case Report Research

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Alcohol Use Disorders in Primary Care
Rounds in the General Hospital

May 21, 2026

Patients with major depressive disorder and a comorbid AUD often present with more severe manifestations, including thoughts of suicide, co-occurring personality disorders, and higher rates of smoking.
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JCP
Effect of a Nationwide Aftercare Program for Self-Harm Presentations on the Risk of Self-Harm Repetition and Suicide
Original Research

May 20, 2026

Aftercare following self-harm was associated with increased risk of repeat self-harm hospital presentation and decreased risk of suicide.
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JCP
Differential Impact of Cholecystokinin and Ghrelin on 2-Year Avoidant/Restrictive Food Intake Disorder Symptoms
Original Research

May 20, 2026

Decreases in CCK and increases in ghrelin were associated with improvements in ARFID symptomology.
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PCC
Diphenhydramine and Dextromethorphan Overdose
Case Report

April 28, 2026

The authors describe a case of intentional overdose with diphenhydramine and extended-release dextromethorphan-guaifenesin that initially presented with anticholinergic toxicity and later evolved into serotonin toxicity.
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PCC
Psychotropic-Induced Reversible Cerebral Vasoconstriction Syndrome
Case Report

April 23, 2026

This case reinforces the importance of monitoring for acute neurologic symptoms in patients treated with high-dose selective serotonin reuptake inhibitors.
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PCC
Osmotic Demyelination Syndrome Presenting as EPS
Case Report

April 21, 2026

A 44-year-old woman was initially referred for presumed domperidone-induced extrapyramidal symptoms, but further workup uncovered a complex interplay of hyponatremia, demyelination, and neuroleptic hypersensitivity.
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PCC
Cultural Manifestations of Bereavement in a Chinese American Patient
Case Report

April 16, 2026

The authors highlight the difficulties of applying western psychiatric concepts to cultural minorities, as seen in a case of complicated bereavement in a 54-year-old Chinese American woman.
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PCC
7-OH-Mitragynine–Induced Psychosis
Case Report

April 14, 2026

The authors present the case of a patient who developed psychosis and delirium following several months of heavy 7-OH use that persisted for nearly a week following cessation.
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PCC
Acitretin, Homocysteine, and Neuropsychiatric Symptoms
Case Report

April 14, 2026

This report describes a case of acitretin-associated hyperhomocysteinemia that induced neuropsychiatric symptoms in a patient with chronic plaque psoriasis, highlighting the need for monitoring.
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