Headaches

Headaches, while primarily a neurological concern, can have significant psychiatric implications. Chronic pain can lead to mood disturbances, anxiety, and other mental health challenges. The Journal of Clinical Psychiatry provides a holistic view of the intersection between headaches and psychiatric conditions. Our expert editors curate content that offers insights into the psychological impact of chronic pain and evidence-based strategies for holistic patient care.

Recently published articles about Headache

Psychotropic-Induced Reversible Cerebral Vasoconstriction Syndrome

Case Report

Psychotropic-Induced Reversible Cerebral Vasoconstriction Syndrome

April 23, 2026

This case reinforces the importance of monitoring for acute neurologic symptoms in patients treated with high-dose selective serotonin reuptake inhibitors.

Michelle Savoldy, Katarina Bojkovic, Cory Klippel, et al

When a Headache Isn’t Just a Headache

Case Report

When a Headache Isn’t Just a Headache

October 7, 2025

A 70-year-old woman experienced progressive headache and systemic symptoms after several days of high-dose ibuprofen administration.

Ananya Narasimhan, Ishani Deshpande, Pavan Kumar Reddy Kalluru, et al

Reversible Cerebral Vasoconstriction Syndrome and Marijuana

Letter to the Editor

Reversible Cerebral Vasoconstriction Syndrome and Marijuana

July 22, 2025

The authors raise awareness of a potential complication of extensive marijuana use.

Jasleen Kaur, Vania Modesto-Lowe, Klaudia Toma

Recurrence of Tolosa-Hunt Syndrome

Case Report

Recurrence of Tolosa-Hunt Syndrome

September 3, 2024

The authors present a unique presentation of ipsilateral recurrence of Tolosa Hunt syndrome involving the sixth cranial nerve in a 64-year-old man.

Harshit Arora, Vasudha Sharma, Lavanya Arora, et al

Why Red Wine Causes Such Banging Headaches

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Why Red Wine Causes Such Banging Headaches

November 27, 2023

A chemical found in red wine may be the reason even a few sips can cause headaches, even when other alcoholic beverages aren't an issue.

FDA Moves to Ban BVO Amid Neurological And Other Health Concerns

news

FDA Moves to Ban BVO Amid Neurological And Other Health Concerns

November 6, 2023

The FDA is proposing a ban on brominated vegetable oil (BVO) following studies that link it to neurological harm and other concerns.

Recent JCP Articles on Headache

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The Receptor at the Center of Psychedelic Therapies for GAD

August 1, 2026

Classic psychedelics target 5-HT2A receptors, not serotonin transporters. Slow dissociation and intracellular signaling may explain lasting effects seen in GAD.

Testosterone-Induced Psychosis in Klinefelter Syndrome

Case Report

Testosterone-Induced Psychosis in Klinefelter Syndrome

July 30, 2026

The authors report a rare case of acute psychosis following long-term parenteral testosterone replacement in a patient with undiagnosed Klinefelter syndrome.

Abhijeet Anand, Shobit Garg

Abrupt Smoking Cessation With Tirzepatide

Case Report

Abrupt Smoking Cessation With Tirzepatide

July 30, 2026

The authors present a case of sudden, sustained smoking cessation associated with the initiation of tirzepatide in a 53-year-old woman.

Omar I. Ceesay, Blase Rokusek, Jordan Rasmussen, et al

Recent PCC Articles on Headache

What's Next for PPD Treatment | Inhaled Mebufotenin (GH001) Phase 2a Results

Webinar

What's Next for PPD Treatment | Inhaled Mebufotenin (GH001) Phase 2a Results

July 29, 2026

Kristina Deligiannidis, MD, presents phase 2a results for inhaled GH001 (mebufotenin), a psychedelic-based therapeutic that produced same-day remission of postpartum depression in an open-label trial, with rapid clearance from...

Exposure-Based Video Therapy for OCD and PTSD

Original Research

Exposure-Based Video Therapy for OCD and PTSD

July 29, 2026

Among patients receiving exposure-based video therapy, 67.4% achieved PTSD response, and 64.1% achieved OCD response.

Nicholas R. Farrell, Clare C. Beatty, Andreas Rhode, et al

Decision-Making Capacity in the Operating Room

Case Report

Decision-Making Capacity in the Operating Room

July 28, 2026

This case illustrates that patients may retain decision-making even when refusing life-sustaining interventions in emergent contexts

Greg Noe, Garret Hill, Hannah Lee, et al

Featured Headache Research

Amiodarone-Induced Thyrotoxicosis and Mania

Case Report

Amiodarone-Induced Thyrotoxicosis and Mania

July 28, 2026

A 66-year-old man diagnosed with amiodarone-induced thyrotoxicosis who presented to the emergency department with symptoms of mania.

David R. Spiegel, Rachel Billingsly, Melissa Cazzell, et al

Turning Stigma Into Stories of Hope with Aderonke Pederson, MD

Podcast

Turning Stigma Into Stories of Hope with Aderonke Pederson, MD

July 28, 2026

Dr. Aderonke Pederson on contact-based storytelling to reduce mental illness stigma, address medical mistrust, and improve care engagement in Black adults.

Aderonke Pederson, Ben Everett

APA 2026: Real-World Gaps in GAD Care and Early Safety Data for DT120

news

APA 2026: Real-World Gaps in GAD Care and Early Safety Data for DT120

July 27, 2026

APA 2026 data show GAD treatment cycling is common, while preclinical DT120 studies address cardiac and dependence safety concerns for this 5-HT2A agonist.