Headaches

Headaches, while primarily a neurological concern, can have significant psychiatric implications. Chronic pain can lead to mood disturbances, anxiety, and other mental health challenges. The Journal of Clinical Psychiatry provides a holistic view of the intersection between headaches and psychiatric conditions. Our expert editors curate content that offers insights into the psychological impact of chronic pain and evidence-based strategies for holistic patient care.

Recently published articles about Headache

Psychotropic-Induced Reversible Cerebral Vasoconstriction Syndrome

Case Report

Psychotropic-Induced Reversible Cerebral Vasoconstriction Syndrome

April 23, 2026

This case reinforces the importance of monitoring for acute neurologic symptoms in patients treated with high-dose selective serotonin reuptake inhibitors.

Michelle Savoldy, Katarina Bojkovic, Cory Klippel, et al

When a Headache Isn’t Just a Headache

Case Report

When a Headache Isn’t Just a Headache

October 7, 2025

A 70-year-old woman experienced progressive headache and systemic symptoms after several days of high-dose ibuprofen administration.

Ananya Narasimhan, Ishani Deshpande, Pavan Kumar Reddy Kalluru, et al

Reversible Cerebral Vasoconstriction Syndrome and Marijuana

Letter to the Editor

Reversible Cerebral Vasoconstriction Syndrome and Marijuana

July 22, 2025

The authors raise awareness of a potential complication of extensive marijuana use.

Jasleen Kaur, Vania Modesto-Lowe, Klaudia Toma

Recurrence of Tolosa-Hunt Syndrome

Case Report

Recurrence of Tolosa-Hunt Syndrome

September 3, 2024

The authors present a unique presentation of ipsilateral recurrence of Tolosa Hunt syndrome involving the sixth cranial nerve in a 64-year-old man.

Harshit Arora, Vasudha Sharma, Lavanya Arora, et al

Why Red Wine Causes Such Banging Headaches

news

Why Red Wine Causes Such Banging Headaches

November 27, 2023

A chemical found in red wine may be the reason even a few sips can cause headaches, even when other alcoholic beverages aren't an issue.

FDA Moves to Ban BVO Amid Neurological And Other Health Concerns

news

FDA Moves to Ban BVO Amid Neurological And Other Health Concerns

November 6, 2023

The FDA is proposing a ban on brominated vegetable oil (BVO) following studies that link it to neurological harm and other concerns.

Recent JCP Articles on Headache

In Loving Memory of Scott A. Freeman, MD

In Memoriam

In Loving Memory of Scott A. Freeman, MD

November 10, 2026

JCP’s Editor in Chief remembers her husband, Scott A. Freeman, MD, and urges greater attention to chronic pain and its link to suicide.

Marlene P. Freeman

In Memoriam: Scott A. Freeman, MD

In Memoriam

In Memoriam: Scott A. Freeman, MD

November 10, 2026

Scott A. Freeman, MD, is remembered for his expertise in psychopharmacology and his commitment to caring for severely ill patients.

Mark Hyman Rapaport

Organ Transplantation in Autism

Rounds in the General Hospital

Organ Transplantation in Autism

November 10, 2026

Hospitalization following organ transplant can be challenging, and patients with autism spectrum disorder may be even more frightened by these experiences, complicating the recovery process.

Diego Nolasco, Filza Hussain, Yelizaveta Sher, et al

Recent PCC Articles on Headache

Severe Phenibut Withdrawal

Case Report

Severe Phenibut Withdrawal

November 10, 2026

The authors describe a case of a 23-year-old woman illustrating the severity and diagnostic complexity of phenibut withdrawal.

Camilla Mancuso, Alejandro Rodulfo, Jason Vayner, et al

Functional Unblinding and Its Implications for the Internal Validity of RCTs

Clinical and Practical Psychopharmacology

Functional Unblinding and Its Implications for the Internal Validity of RCTs

November 9, 2026

This article discusses blinding, the need for blinding, indices suggested for quantifying the integrity of blinding, questions that need to be asked to assess blinding, why assessing blinding only...

Chittaranjan Andrade

The ASCP Task Force Consensus Statement on Combination Psychopharmacology

Consensus Statement

The ASCP Task Force Consensus Statement on Combination Psychopharmacology

November 9, 2026

Expert guidance to help practitioners identify clinically driven principles that shape coherent multi-drug regimens.

Joseph F. Goldberg, Gin S. Malhi, Manish K. Jha, et al

Featured Headache Research

Treatment-Resistant Depression as a Dynamic Continuum

Clinical Pearls

Treatment-Resistant Depression as a Dynamic Continuum

November 6, 2026

Seven questions on treatment-resistant depression: early recognition, adequate trials, mechanistic sequencing, and when to refer.

Gastrointestinal Adverse Events After 5 and 52 Weeks of Xanomeline-Trospium in Inpatients and Outpatients

Clinical Pearls

Gastrointestinal Adverse Events After 5 and 52 Weeks of Xanomeline-Trospium in Inpatients and Outpatients

November 6, 2026

When gastrointestinal events appear with xanomeline-trospium: onset, duration, and discontinuation across 5-week and 52-week trials.

Efficacy Outcomes After 5 and 52 Weeks of Xanomeline-Trospium in Inpatients and Outpatients

Clinical Pearls

Efficacy Outcomes After 5 and 52 Weeks of Xanomeline-Trospium in Inpatients and Outpatients

November 6, 2026

Two trials, two populations: xanomeline-trospium PANSS and CGI-S outcomes at 5 weeks in inpatients and 52 weeks in outpatients, and why they differ.