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Case Report

A Case of Acute Psychosis After Buprenorphine Withdrawal: Abrupt Versus Progressive Discontinuation Could Make a Difference

Sébastien Weibel, MD; Martial Mallaret, MSc; Mehdi Bennouna-Greene, MD; and Gilles Bertschy, MD, PhD

Published: June 15, 2012

Article Abstract

Because this piece does not have an abstract, we have provided for your benefit the first 3 sentences of the full text.

Buprenorphine, a partial μ-opioid agonist and κ-opioid antagonist, is frequently used in the treatment of heroin dependence and to prevent complications arising from intravenous injection and social consequences of heroin use. Psychosis occurring after discontinuation of buprenorphine or other opioids has been described, but is uncommon.

Case report. Mr A, a 37-year-old man, was admitted to our psychiatric ward for acute psychotic symptoms with mystical and paranoid delusions and intense auditory hallucinations.

J Clinical Psychiatry 2012; 73(6): 765

© 2012 Physicians Postgraduate Press, Inc.’ ‹’ ‹

Volume: 73

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