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Academic Highlights

Clinical Insights Into Pharmacogenetics and Schizophrenia, Part 1

John M. Kane, MD; Roy H. Perlis, MD, PhD; and Anil K. Malhotra, MD

Published: March 14, 2008

Article Abstract

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Schizophrenia is a heterogeneous disorder in terms of course and treatment response. The field of pharmacogenetics, which seeks to reveal how genetic factors affect patients’ response to drugs, holds promise to help clinicians develop a better understanding of antipsychotic therapy,1 such as which patients might respond better or worse to specific agents or treatment in general or which patients might be at particular risk for serious adverse effects.

What do practicing psychiatrists need to know about using genetic tests?

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