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ASCP Corner

Gender Differences in Clinical Psychopharmacology

Anita H. Clayton, MD

Published: September 15, 2005

Article Abstract

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Biological differences between men andwomen appear, at least in part, to be related tovariation in levels and changes in sex steroidsthat subsequently interact with neurotransmitters.Reproductive-aged women have repetitivevariations in sex hormones with eachmonthly cycle that influence the onset, chronicity,and outcome of a variety of psychiatricillnesses. Variations in brain structure and functionand in pharmacokinetics may also contributeto psychiatric outcomes.’ ‹

Volume: 66

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