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Letter to the Editor

Low-Dose Risperidone and Quetiapine as Monotherapy for Comorbid Anxiety and Depression

Igor Galynker, MD, PhD; Asim Khan, MD; Yuli Grebchenko, MD; Aleksey Ten, MD; Liliya Malaya, PhD; Philip Yanowitch, MD; and Lisa J. Cohen, PhD

Published: April 15, 2005

Article Abstract

Because this piece has no abstract, we have provided for your benefit the first 3 sentences of the full text.

Sir: Up to 80% of patients with generalized anxiety disorder(GAD) suffer from a comorbid mood disorder.1 Atypical antipsychoticsare frequently prescribed as off-label adjunctivetreatment for GAD and major depressive disorder (MDD); however,no studies have demonstrated the effectiveness of thesedrugs as monotherapy.2,3 Here, we present a case series describingthe use of risperidone and quetiapine as monotherapy forGAD and MDD.’ ‹’ ‹

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