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The Journal of
Clinical Psychiatry
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The Journal of Clinical Psychiatry

Letter to the Editor December 15, 2006

Onset of Unipolar Depression or Bipolar Depression Prior or Close to Menarche

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J Clin Psychiatry 2006;67(12):2032-2032

Article Abstract

Letter to the Editor

Onset of Unipolar Depression or Bipolar Depression Prior or Close to Menarche

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New Series The JCP Podcast Lamotrigine clearance can rise by 200% to 300% in pregnancy, turning a previously stable dose into therapeutic failure, while the postpartum reset can make that same dose toxic fast. This conversation gets practical about monitoring, tapering, and why screening for bipolar disorder in postpartum depression can change treatment decisions.

 

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