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Letter to the Editor

Reply to “It looks like “Bradyphylaxis” to Me.”

David A. Solomon, MD

Published: August 15, 2005

Article Abstract

Because this piece has no abstract, we have provided for your benefit the first 3 sentences of the full text.

Sir: I thank Dr. Jefferson for his interest in our work,1 whichdescribed recurrences of major depression despite full doses ofmaintenance medication. We observed such recurrences in 25%of the cases in which study subjects were maintained on theirantidepressant therapy after successful treatment for an episodeof major depression. The morbidity and impairment associatedwith these recurrences can be devastating.’ ‹

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Volume: 66

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