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Letter to the Editor

Resolution of Fluoxetine-Induced Sexual Dysfunction With the 5-HT3 Antagonist Granisetron

Erik B. Nelson, Paul E. Keck, Jr., and Susan L. McElroy

Published: November 15, 1997

Article Abstract

Letter to the Editor

Sir: Sexual dysfunction is a common and troubling side effect
of serotonin reuptake inhibitors (SRIs). The incidence of
sexual dysfunction associated with SRIs has been estimated to be
as high as 34%. The mechanism underlying sexual dysfunction
associated with SRIs has not been fully characterized, but is
thought to be partly mediated by direct serotonergic effects.

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