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Symptoms of Fatigue and Cognitive/Executive Dysfunction in Major Depressive Disorder Before and After Antidepressant Treatment

Maurizio Fava, MD

Published: October 1, 2003

Article Abstract

Patients with major depressive disorder commonly experience fatigue and cognitive/executivedysfunction. These problems may be symptoms of the depression and persist despite effective antidepressanttreatment, or these problems may emerge as adverse effects of some antidepressanttreatments. A number of augmentation strategies can be employed to manage fatigue or cognitive/executive dysfunction, but the efficacy of these augmentation strategies must be researched further.

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