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Letter to the Editor

Toxic Catatonia Secondary to Azithromycin

Maria Teresa Plana, Jordi Blanch, Soledad Romero, Montserrat Serra, and Cristobal Gasto

Published: March 15, 2006

Article Abstract

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Sir: Several publications report psychiatric symptoms induced by macrolide antibiotics. Clarithromycin and erythromycin used in combination with other treatments, or even in monotherapy, have been reported to produce acute psychoses,1-6 manic episodes,7-12 and depression.13 To our knowledge, this is the first report of an association between azithromycin, another macrolide antibiotic, and the initiation of acute psychotic depression with catatonic symptoms.’ ‹’ ‹

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Volume: 67

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