5 Minute Pearls

Recently published articles about 5 Minute Pearls

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October 31, 2023

A gender affirming approach to mental healthcare involves believing and honoring whom our patients tell us that they are and providing services that affirm them in their gender identity...
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August 31, 2023

Dr. Christina Cusin reviews ketamine for depression and suicidality, including patient suitability, administration, treatment duration, and drug compatibility.
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July 20, 2023

Psychiatrist George Papakostas, MD shares five essential ways to manage major depressive disorder to optimize treatment success for patients.
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July 6, 2023

In this 5 Minute Pearls video, psychiatrist Aderonke Pederson, MD shares clinically relevant insights for why it's important to address mental illness stigma in an open way with patients.
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June 15, 2023

A metamorphic revolution is happening in psychiatry, led by psychedelic therapy and MDMA. Scott Aaronson, MD explores the therapeutic benefits.
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May 25, 2023

Marlene Freeman, MD shares the latest clinically relevant updates for postpartum depression and other postpartum psychiatric disorders.

Recent JCP Articles on 5 Minute Pearls

PCC
ECT for Psychosis in Huntington Disease-Like 2
Case Report

May 19, 2026

A 47-year-old woman with genetically confirmed Huntington disease-like 2 had refractory psychosis and functional decline but responded well to electroconvulsive therapy.
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PCC
Manifestations Associated With CNS Lesions
Rounds in the General Hospital

May 19, 2026

Neuropsychiatric manifestations of brain metastases are varied, although certain symptoms can be associated with the brain region in which there is a metastasis; lesions that affect certain parts of...
, , , et al
JCP
Rethinking Postpartum Depression: Biology, Biomarkers, and New Treatments with Jennifer L. Payne, MD
Podcast

May 19, 2026

Jennifer L. Payne, MD, discusses postpartum depression biomarkers, allopregnanolone and GABA-A receptor biology, and the clinical profile of zuranolone.
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Recent PCC Articles on 5 Minute Pearls

JCP
Systematic Review and Meta-Analysis of Use of Mood Stabilizers in Adolescents With Nonsuicidal Self-Injury
Meta-Analysis

May 18, 2026

Severity of anxiety, depression, impulsivity, and self-injury was significantly reduced following treatment with mood stabilizers.
, , , et al
PCC
Peer Support to Prevent Suicide Among Medical Students
Letter to the Editor

May 14, 2026

The authors describe a peer support panel discussion designed to address suicide prevention, allowing medical students to actively participate in addressing critical mental health challenges they face in their...
, , , et al
PCC
Adjunct Memantine for Inappropriate Sexual Behavior
Case Report

May 14, 2026

Two patients with intellectual disability and major neurocognitive disorder exhibited inappropriate sexual behavior that significantly decreased after memantine was added as adjunctive therapy.
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Featured 5 Minute Pearls Research

PCC
From Physical to Digital: Hoarding Phenomena in Obsessive-Compulsive Disorder
Case Report

May 14, 2026

This case illustrates how hoarding phenomenology can manifest in digital environments, which offer virtually unlimited storage, anonymity, and low visibility.
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JCP
NNT, NNH, and LLH for Aripiprazole Once-Monthly in Schizophrenia
Original Research

May 13, 2026

Data demonstrate a favorable benefit-risk profile for aripiprazole once-monthly 400 vs placebo in acute and maintenance treatment of schizophrenia.
, , , et al
JCP
Efficacy and Safety of a Single Dose of Psilocybin for Chronic Suicidal Ideation
Original Research ▶ Video

May 13, 2026

A single psilocybin dose with psychological support was associated with rapid, large, and durable reductions in suicidal ideation and depressive symptoms.
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