A Case of Fluoxetine-Induced Lower Extremity Ecchymosis

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To the Editor: Fluoxetine is a selective serotonin reuptake inhibitor (SSRI) mainly prescribed in the treatment of depression, anxiety disorders, bulimia nervosa, and premenstrual syndrome. Although SSRIs have been reported to potentially be associated with an increased risk of bleeding, fluoxetine-induced ecchymosis is rare, with few cases in the current literature. We report the case of a female patient who manifested lower-extremity ecchymosis related to fluoxetine use.