The Primary
Care Companionfor CNS Disorders

Advancing primary care with essential peer-reviewed research and insights into CNS disorders

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More Articles from The Primary Care Companion for DNS Disorders

PCC
Agitation and an Altered Mental Status in the ED
Rounds in the General Hospital

December 8, 2022

Mr A was brought to the ED by police due to increasingly irritable and disturbing behavior for the last month. This Rounds report provides guidance on managing altered mental…
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PCC
Psychosis Associated With Tacrolimus
Case Report

December 8, 2022

A 37-year-old man developed acute paranoid psychosis 7 months after renal transplantation, possibly induced by tacrolimus at therapeutic serum levels.
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PCC
A Review of the Midlevel Care Provider System in New York State
Brief Report

December 6, 2022

The gaps in the provision of mental health care are slowly increasing, and innovative solutions are needed to address these needs. Midlevel providers may be the solution to address…
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PCC
hs-CRP as a Biomarker and Endophenotype in Mania
Original Research

December 6, 2022

Blood hs-CRP level is a biomarker in mania and may be a newer approach to detect disease progression and guide novel therapies.
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PCC
ECT in Children With Lupus Cerebritis and Catatonia
Case Report

December 1, 2022

A 13-year-old girl with neuropsychiatric systemic lupus erythematosus presenting with psychosis and persistent catatonia unresponsive to immunosuppressive agents and a benzodiazepine was successfully treated with ECT.
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PCC
COVID-19 Near-Death Experience
Case Report

December 1, 2022

This middle-aged man with no history of psychiatric illness was hospitalized in the ICU for COVID-19 respiratory symptoms. Although he did not need ventilation or resuscitation, he experienced “death”…
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PCC
Pharmacist-Led Dementia Care Rounds and Sleep Medication Use
Original Research

November 29, 2022

Pharmacist-led dementia care rounds are an efficient way to correct sleep medication use and can contribute to benzodiazepine discontinuation, which is especially important in the elderly.
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PCC
An Update on the Future of Wilson Disease Management
Commentary

November 29, 2022

Due to Wilson disease myriad manifestations, its rarity, and its range of symptoms, differential diagnosis may be challenging, leading to delays in treatment. This Neuroscience Commentary reviews diagnostic acumen…
PCC
High-Dose Therapy in Treatment-Refractory Psychosis
Original Research

November 24, 2022

In forensic patients hospitalized in a long-term psychiatric facility, antipsychotic dose reduction had a positive effect on treatment effectiveness, competency restoration, and hospital discharge with no symptom relapse.
PCC
Therapeutic Dilemma of Wake-up Stroke
Original Research

November 24, 2022

The importance of recognizing wake-up stroke for early referral to acute stroke care is highlighted in this study, as patients may benefit from acute reperfusion therapy after obtaining the…
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PCC
Impairment of Sexual Desire in Treatment-Resistant Depression
Original Research

November 22, 2022

Patients with treatment-resistant depression had a high prevalence of sexual desire impairment, which was associated with male sex and higher depressive symptom severity.
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PCC
Recreational Use of 2M2B
Case Report

November 22, 2022

This report describes a patient whose use of 2-methyl-2-butanol—an inexpensive, easily accessible, potent, and nondetectable ethanol substitute—led to protracted intoxication and delirium.
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Consensus Report on XT Use in Practice

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Figure: Graphic promoting Consensus Report on Xanomeline-Trospium; colorful net design shown with JCP logo in lower left.

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