This work may not be copied, distributed, displayed, published, reproduced, transmitted, modified, posted, sold, licensed, or used for commercial purposes. By downloading this file, you are agreeing to the publisher’s Terms & Conditions.

Letter to the Editor

Comment on Palinacousis or Auditory Perseverations and COVID-19 Vaccination

Amnuay Kleebayoon, PhD, and Viroj Wiwanitkit, MD

Published: June 27, 2023

See article by Mendez

To the Editor: We would like to share ideas on the report “Palinacousis or Auditory Perseverations Following COVID-19 Vaccination” recently published in the PCC.1 In the case report, a patient developed palinacousis after receiving the COVID-19 vaccination.1 According to the authors,1 clinicians may need to take auditory illusions into account in addition to the frequently reported neurologic side effects in patients receiving COVID-19 vaccines.

Sometimes, due to lack of knowledge, it can be difficult to pinpoint the exact patho-immuno-pharmacologic connection. It might be difficult to understand how enduring medical conditions affect clinical practice. The previously unidentified COVID-19 virus2 is another confounder that should send up red flags. With prior COVID-19 infection, the results and the vaccine’s efficacy might have been different. It is typically impossible to completely rule out the impact of earlier asymptomatic disorders without the required laboratory testing. Genetics is another crucial factor.3 The negative effects of vaccination may vary depending on how the immune system responds to particular hereditary components. Examination of the underlying genetic component would greatly aid in drawing conclusions about the clinical link, and attention should be given to this issue in future research.

Dr Mendez was shown this letter and declined to comment.

Article Information

Published Online: June 27, 2023.
© 2023 Physicians Postgraduate Press, Inc.
Prim Care Companion CNS Disord. 2023;25(3):23lr03523
Submitted: March 11, 2023.
To Cite: Kleebayoon A, Wiwanitkit V. Comment on palinacousis or auditory perseverations and COVID-19 vaccination. Prim Care Companion CNS Disord. 2023;25(3):23lr03523.
Author Affiliations: Private Academic Consultant, Samraong, Cambodia (Kleebayoon); Chandigarh University, Punjab, India (Wiwanitkit); Joesph Ayobabalola University, Ikeji-Arakeji, Nigeria (Wiwanitkit).
Corresponding Author: Amnuay Kleebayoon, PhD, 127 Main Rd, Samraong Oddar Meanchey 210307 Cambodia (
Relevant Financial Relationships: None.
Funding/Support: None.

Volume: 25

Quick Links:


Buy this Article as a PDF