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Care Companionfor CNS Disorders
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Primary Care Companion for CNS Disorders

Letter to the Editor June 16, 2008

A Case of Lamotrigine-Associated Anticonvulsant Hypersensitivity Syndrome

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Prim Care Companion J Clin Psychiatry 2008;10(3):249-250

Article Abstract

Letter to the Editor

A Case of Lamotrigine-Associated Anticonvulsant-Hypersensitivity Syndrome

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New Series The JCP Podcast Lamotrigine clearance can rise by 200% to 300% in pregnancy, turning a previously stable dose into therapeutic failure, while the postpartum reset can make that same dose toxic fast. This conversation gets practical about monitoring, tapering, and why screening for bipolar disorder in postpartum depression can change treatment decisions.

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